Anne P.M. Atkinson
Scottish National Blood Transfusion Service
13 Papers
158 Citations
Anne P.M. Atkinson is an academic researcher from Scottish National Blood Transfusion Service. The author has contributed to research in topics: Mannan-binding lectin & Lectin pathway. The author has an hindex of 11, co-authored 13 publications.
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Papers
Granulocyte colony-stimulating factor and autologous CD133-positive stem-cell therapy in liver cirrhosis (REALISTIC): an open-label, randomised, controlled phase 2 trial
Philip N. Newsome,Philip N. Newsome,Richard Fox,Richard Fox,Andrew King,Andrew King,Darren Barton,Darren Barton,Nwe-Ni Than,Nwe-Ni Than,Joanna Moore,Chris Corbett,Sarah Townsend,James Thomas,Kathy Guo,Kathy Guo,Diana Hull,Diana Hull,Heather A Beard,Jacqui Thompson,Anne P.M. Atkinson,Carol Bienek,Neil W. A. McGowan,Neil Guha,John D.M. Campbell,Dan Hollyman,Deborah Stocken,Christina Yap,Stuart J. Forbes +28 more
TL;DR: G-CSF with or without haemopoietic stem-cell infusion did not improve liver dysfunction or fibrosis and might be associated with increased frequency of adverse events compared with standard care.
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L-ficolin in children with recurrent respiratory infections
Anne P.M. Atkinson,Maciej Cedzynski,Janusz Szemraj,A. St. Swierzko,Leokadia Bak-Romaniszyn,Małgorzata Banasik,Krzysztof Zeman,Misao Matsushita,Marc Turner,David C. Kilpatrick +9 more
TL;DR: In this article, the lectin pathway of complement activation is used by a collectin, mannan-binding lectin (MBL), and two ficolins, L-ficolin, to opsonize microorganisms for phagocytosis.
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Two factors of the lectin pathway of complement, l-ficolin and mannan-binding lectin, and their associations with prematurity, low birthweight and infections in a large cohort of Polish neonates.
Anna St. Swierzko,Anne P.M. Atkinson,Maciej Cedzynski,Shirley Lynn Macdonald,Agnieszka Szala,Iwona Domzalska-Popadiuk,Monika Borkowska-Klos,Aleksandra Jopek,Jerzy Szczapa,Misao Matsushita,Janusz Szemraj,Marc Turner,David C. Kilpatrick +12 more
TL;DR: It is suggested that l-ficolin participates in host defence during the perinatal period and constitute the first evidence that relative l- ficolin deficiency may contribute to the adverse consequences of prematurity.
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Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis.
Alasdair R. Fraser,Chloe Pass,Paul Burgoyne,Anne P.M. Atkinson,Laura Bailey,Audrey Laurie,Neil W. A. McGowan,Akib Hamid,Joanna Moore,Benjamin J. Dwyer,Marc Turner,Marc Turner,Stuart J. Forbes,John D. M. Campbell,John D. M. Campbell +14 more
TL;DR: This is the first report of validation of a large-scale, fully Good Manufacturing Practice–compliant, autologous macrophage cell therapy product for the potential treatment of cirrhosis, and shows that the cell product in excipient is remarkably robust, consistently passing the viability and phenotypic release criteria up to 48 hours after harvest.
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Mannan-binding lectin-associated serine protease-2 (MASP-2) in a large cohort of neonates and its clinical associations.
Anna St. Swierzko,Maciej Cedzynski,Iwona Domzalska-Popadiuk,Shirley Lynn Macdonald,Monika Borkowska-Klos,Anne P.M. Atkinson,Agnieszka Szala,Aleksandra Jopek,Jens C. Jensenius,Masaya Kawakami,Jerzy Szczapa,Misao Matsushita,Janusz Szemraj,Marc Turner,David C. Kilpatrick +14 more
TL;DR: Serum MASP-2 concentrations correlated with gestational age and birthweight and were significantly lower in premature babies and other pre-term babies compared with term babies, and there was a trend towards higherMASP-1 concentrations amongst babies with infections, and no association of this SNP was apparent with prematurity, low birthweight or perinatal infections.
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