Anna Whitehead
University of Leeds
11 Papers
11 Citations
Anna Whitehead is an academic researcher from University of Leeds. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 4 publications.
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Papers
Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis.
Anna Whitehead,Fynn N. Krause,Amy Moran,Amanda D. V. MacCannell,Jason L. Scragg,Ben D. McNally,Edward Boateng,Steven A. Murfitt,Samuel Virtue,John Wright,Jack Garnham,Graeme Davies,James Dodgson,Jürgen E. Schneider,Andrew J. Murray,Christopher Church,Antonio Vidal-Puig,Klaus K. Witte,Julian L. Griffin,Lee D. Roberts +19 more
TL;DR: This article identified 3-methyl-2-oxovaleric acid, 5-oxoproline, and β-hydroxyisobutyric acid as small molecule metabokines synthesized in browning adipocytes and secreted via monocarboxylate transporters.
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle
Ben D. McNally,Dean F Ashley,Lea Hänschke,Helene Nissrine Daou,Nicole T. Watt,Steven A. Murfitt,Amanda D. V. MacCannell,Anna Whitehead,T. Scott Bowen,Francis Sanders,Michele Vacca,Klaus Witte,Graeme Davies,Reinhard Bauer,Julian L. Griffin,Lee D. Roberts +15 more
TL;DR: In this article , the endoplasmic reticulum (ER) regulates cellular protein and lipid biosynthesis, which leads to protein misfolding and the unfolded protein response (UPR), which limits protein synthesis to prevent cytotoxicity.
Chronic heart failure with diabetes mellitus is characterized by a severe skeletal muscle pathology.
Jack Garnham,Lee D. Roberts,Ever Espino-Gonzalez,Anna Whitehead,Peter P Swoboda,Aaron Koshy,John Gierula,Maria F. Paton,Richard M Cubbon,Mark T. Kearney,Stuart Egginton,T. Scott Bowen,Klaus K. Witte +12 more
TL;DR: The skeletal muscle phenotype and its relationship to exercise limitation in patients with diabetic heart failure (D‐HF) and diabetes mellitus is characterized.
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Sexual dimorphism in adipose tissue mitochondrial function and metabolic flexibility in obesity.
Amanda D. V. MacCannell,T. Simon Futers,Anna Whitehead,Amy Moran,Klaus K. Witte,Lee D. Roberts +5 more
TL;DR: In this article, male and female mice fed high fat diet (HFD) or standard diet (STD) from 8-18 weeks of age underwent whole animal calorimetry and high-resolution mitochondrial respirometry analysis on adipose tissue depots.
Sex-Dependent Effects of Inhaled Nicotine on the Gut Microbiome.
Anna Whitehead,Margaret C Meyers,Christopher M. Taylor,Meng Luo,Scot E. Dowd,Xinping Yue,Lauri O. Byerley +6 more
TL;DR: It is demonstrated that nicotine inhalation alters the gut microbiome in a sex-specific manner, which may contribute to the adverse health consequences of inhaled nicotine.
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