Anna Vavřínová
Academy of Sciences of the Czech Republic
14 Papers
8 Citations
Anna Vavřínová is an academic researcher from Academy of Sciences of the Czech Republic. The author has contributed to research in topics: Adrenal medulla & Spontaneously hypertensive rat. The author has an hindex of 5, co-authored 12 publications. Previous affiliations of Anna Vavřínová include Charles University in Prague.
Chat about Author
Papers
Ontogenetic changes in contribution of calcium sensitization and calcium entry to blood pressure maintenance of Wistar-Kyoto and spontaneously hypertensive rats.
Michal Behuliak,Anna Vavřínová,Michal Bencze,Kamila Polgárová,Peter Ergang,Jaroslav Kuneš,Ivana Vaněčková,Josef Zicha +7 more
TL;DR: The importance of RhoA/Rho-kinase pathway for BP/vascular tone control is attenuated in SHR from prehypertensive stages as indicated by the ratio between fasudil-induced and nifedipine-induced BP changes was lower in all age groups of SHR compared with WKY.
23
Sympathectomy-induced blood pressure reduction in adult normotensive and hypertensive rats is counteracted by enhanced cardiovascular sensitivity to vasoconstrictors.
Anna Vavřínová,Anna Vavřínová,Michal Behuliak,Michal Bencze,Martin Vodička,Martin Vodička,Peter Ergang,Ivana Vaněčková,Josef Zicha +8 more
TL;DR: Sympathectomy produced a transient decrease in BP, a chronic decrease in HR and improvement in baroreflex sensitivity, and was counteracted by increased vascular sensitivity to catecholamines in W KY rats and SHRs and/or by the enhanced secretion of adrenal hormones, which was more pronounced in WKY rats.
20
Altered contractile responses of arteries from spontaneously hypertensive rat: The role of endogenous mediators and membrane depolarization
TL;DR: Enhanced contractility of SHR arteries is related to both increased presence of endogenous norepinephrine in vascular wall and also to altered vascular smooth muscle membrane potential.
13
The importance of the selection of appropriate reference genes for gene expression profiling in adrenal medulla or sympathetic ganglia of spontaneously hypertensive rat.
TL;DR: Many alterations in expression of catecholaminergic system genes in adrenal medulla and sympathetic ganglia of SHR are found and indicate the importance of appropriate internal control.
8
Which sympathoadrenal abnormalities of adult spontaneously hypertensive rats can be traced to a prehypertensive stage
TL;DR: Surprisingly, downregulation of catecholamine biosynthetic enzymes was observed in both the adrenal medulla and sympathetic ganglia of SHR at both ages, which might be a compensatory mechanism that counteracts the vascular sympathetic hyperinnervation seen in SHR of both ages.
8