Anna-Karin Falck
Lund University
8 Papers
18 Citations
Anna-Karin Falck is an academic researcher from Lund University. The author has contributed to research in topics: Breast cancer & Lymph node. The author has an hindex of 7, co-authored 8 publications.
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Papers
Does Analysis of Biomarkers in Tumor Cells in Lymph Node Metastases Give Additional Prognostic Information in Primary Breast Cancer
TL;DR: In this paper, the concordance between biomarkers in matched pairs of breast cancers and lymph node metastases and to relate their expression to clinical outcome was defined and a tissue microarray of primary tumors and lymph nodes metastases was constructed, and estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and Ki67 were analyzed immunohistochemically in 262, 257, 104, and 101 patients, respectively.
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Analysis of and prognostic information from disseminated tumour cells in bone marrow in primary breast cancer: a prospective observational study
Anna-Karin Falck,Pär-Ola Bendahl,Christian Ingvar,Jorma Isola,Per-Ebbe Jönsson,Pia Lindblom,Kristina Lövgren,Karin Rennstam,Mårten Fernö,Lisa Rydén +9 more
TL;DR: The detection of DTCs in bone marrow in primary breast cancer was previously shown to be a predictor of poor prognosis, and future studies with a standardised patient protocol and improved technique for isolating and detecting D TCs may reveal the clinical applications of D TC detection in patients with micrometastases in the bone marrow.
The combination of Ki67, histological grade and estrogen receptor status identifies a low-risk group among 1,854 chemo-naïve women with N0/N1 primary breast cancer
Carina Strand,Martin Bak,Signe Borgquist,Gunilla Chebil,Anna-Karin Falck,Marie-Louise Fjällskog,Dorthe Grabau,Ingrid Hedenfalk,Karin Jirström,Marie Klintman,Per-Uno Malmström,Hans Olsson,Lisa Rydén,Olle Stål,Pär-Ola Bendahl,Mårten Fernö +15 more
TL;DR: A prognostic index based on a proliferation marker, histological grade, and estrogen receptor (ER) in different subsets of primary N0/N1 chemo-naïve breast cancer patients is confirmed, confirming a low-risk group of patients with N0-N1 primary breast cancer.
•Dissertation
Modern Staging in Primary Breast Cancer-aspects of micrometastatic disease in bone marrow and molecular profiles in lymph node metastases
Anna-Karin Falck
- 01 Jan 2013
TL;DR: The main focus was on evaluating tumour tissue and disseminated cells from different metastatic locations, to analyse the distribution of biomarkers and relate them to the prognosis for individual patients, and support the recommendation that biomarker analysis is performed in loco-regional and distant relapses.
The Three Receptor Tyrosine Kinases c-KIT, VEGFR2 and PDGFRα, Closely Spaced at 4q12, Show Increased Protein Expression in Triple-Negative Breast Cancer
Sara Jansson,Pär-Ola Bendahl,Dorthe Grabau,Anna-Karin Falck,Mårten Fernö,Kristina Aaltonen,Lisa Rydén +6 more
TL;DR: C-KIT, VEGFR2 and PDGFRα show higher protein expression in TNBC compared to non-TNBC, and further investigation clarifying the importance of these RTKs in T NBC is encouraged, as they are possible targets for anticancer therapy.