Anna Häggmark
Royal Institute of Technology
13 Papers
50 Citations
Anna Häggmark is an academic researcher from Royal Institute of Technology. The author has contributed to research in topics: Proteomic Profiling & Biomarker discovery. The author has an hindex of 11, co-authored 13 publications.
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Papers
Autoantibody Profiling in Multiple Sclerosis Using Arrays of Human Protein Fragments
Burcu Ayoglu,Anna Häggmark,Mohsen Khademi,Tomas Olsson,Mathias Uhlén,Jochen M. Schwenk,Peter Nilsson +6 more
TL;DR: Using protein fragments and complementary high-throughput protein array platforms facilitated an alternative route to discovery and verification of potentially disease-associated autoimmunity signatures, that are now proposed as additional antigens for large-scale validation studies across multiple sclerosis biobanks.
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Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex
Evelina Sjöstedt,Linn Fagerberg,Björn M. Hallström,Anna Häggmark,Nicholas Mitsios,Peter Nilsson,Fredrik Pontén,Tomas Hökfelt,Mathias Uhlén,Jan Mulder +9 more
TL;DR: This multi-angle approach uncovered the brain-enriched transcriptome and linked genes to cell types and functions, providing novel insights into the molecular foundation of this highly specialized organ.
Systematic antibody and antigen-based proteomic profiling with microarrays
Burcu Ayoglu,Anna Häggmark,Maja Neiman,Ulrika Igel,Mathias Uhlén,Jochen M. Schwenk,Peter Nilsson +6 more
TL;DR: Some of the current building blocks within array- and affinity-based proteomic profiling with a focus on body fluids are summarized, by giving a perspective on how current and upcoming developments in this bioscience could enable a path of pursuit for biomarker discovery.
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Plasma profiling reveals three proteins associated to amyotrophic lateral sclerosis
Anna Häggmark,Maria Mikus,Atefeh Mohsenchian,Mun-Gwan Hong,Björn Forsström,Beata Gajewska,Anna Barańczyk-Kuźma,Mathias Uhlén,Jochen M. Schwenk,Magdalena Kuźma-Kozakiewicz,Peter Nilsson +10 more
TL;DR: A large number of proteins in plasma from patients with various clinical phenotypes of ALS are analyzed in search of novel proteins or protein profiles that could serve as potential indicators of disease.
Immunocapture strategies in translational proteomics
Claudia Fredolini,Sanna Byström,Elisa Pin,Fredrik Edfors,Davide Tamburro,Maria Jesus Iglesias,Anna Häggmark,Mun-Gwan Hong,Mathias Uhlén,Peter Nilsson,Jochen M. Schwenk +10 more
TL;DR: Some of the field’s current and emerging immunocapture approaches from an affinity proteomics perspective are described, with some of their advantages, pitfalls and opportunities for the next phase in clinical and translational proteomics.
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