Anna Acheva
University of Helsinki
15 Papers
51 Citations
Anna Acheva is an academic researcher from University of Helsinki. The author has contributed to research in topics: DNA damage & Epithelial–mesenchymal transition. The author has an hindex of 6, co-authored 15 publications. Previous affiliations of Anna Acheva include Radiation and Nuclear Safety Authority & Queen's University Belfast.
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Papers
TRPV6 calcium channel directs homeostasis of the mammary epithelial sheets and controls epithelial mesenchymal transition
TL;DR: It is shown that TRPV6 is connected to both E-cadherin-based adherens junctions and intracellular cytoskeletal structures and may compromise homeostasis of the mammary epithelial sheets and may promote the progression of pathophysiological conditions.
Profiling of low molecular weight proteins in plasma from locally irradiated individuals
Reetta Nylund,Elina Lemola,Sonja Hartwig,Stefan Lehr,Anna Acheva,Jutta Jahns,Guido Hildebrandt,Carita Lindholm +7 more
TL;DR: The proteomics techniques applied were unable to identify changes in the proteome of the locally irradiated patients, whereas such differences were observed for the accident victims, thus further studies with more sensitive techniques are warranted.
Clastogenic plasma factors: a short overview
TL;DR: The aim of the paper is to give a short overview on the phenomenon of clastogenic factors—their occurrence and formation as well as possible effectors.
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Assembly of Peripheral Actomyosin Bundles in Epithelial Cells Is Dependent on the CaMKK2/AMPK Pathway
Eeva Kaisa Rajakylä,Jaakko I. Lehtimäki,Anna Acheva,Niccole Schaible,Pekka Lappalainen,Ramaswamy Krishnan,Sari Tojkander +6 more
TL;DR: It is shown that peripheral actomyosin bundles can be generated from a specific actin stress fiber subtype, transverse arcs, through their lateral fusion at cell-cell contacts, and this provides evidence that the mechanosensitive CaMKK2/AMPK pathway is critical for the maintenance of peripheral acton bundles and thus dictates cell- cell junctions through cellular force distribution.
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•Journal Article
Human 3-D tissue models in radiation biology: current status and future perspectives
Anna Acheva,An Aerts,Charlotte Rombouts,Sarah Baatout,Sisko Salomaa,Karin Manda,Guido Hildebrandt,Matus Kämäräinen +7 more
TL;DR: The use of a variety of 3-D models in radiobiological research is discussed and the differences in responses compared to 2-D culturing condiƟ ons (monolayers) are highlighted.
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