Anna Abrahamsson
Karolinska Institutet
9 Papers
139 Citations
Anna Abrahamsson is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Bile acid & Cholic acid. The author has an hindex of 8, co-authored 9 publications.
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Papers
Feedback regulation of bile acid synthesis in primary human hepatocytes: Evidence that CDCA is the strongest inhibitor
Ewa Ellis,Magnus Axelson,Anna Abrahamsson,Gösta Eggertsen,Anders Thörne,Grzegorz Nowak,Bo-Göran Ericzon,Ingemar Björkhem,Curt Einarsson +8 more
TL;DR: G glycine‐conjugated and free bile acids suppress bile acid synthesis and mRNA levels of CYP7A1 in the order CDCA > DCA > CA > UDCA, which is suppressed to a much lower degree than CYP8B1 and CYP27A1.
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Bile acid synthesis in cultured human hepatocytes: support for an alternative biosynthetic pathway to cholic acid
Magnus Axelson,Ewa Ellis,Birgitta Mörk,Kristina Garmark,Anna Abrahamsson,Ingemar Björkhem,Bo-Göran Ericzon,Curt Einarsson +7 more
TL;DR: The results suggest that the observed intermediates reflect an alternative biosynthetic pathway to CA, which may be quantitatively significant in the cells.
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Bile acid synthesis in primary cultures of rat and human hepatocytes
Ewa Ellis,Bryan Goodwin,Anna Abrahamsson,Christopher Liddle,Agneta Mode,Mats Rudling,Ingemar Björkhem,Curt Einarsson +7 more
TL;DR: It is evident that while hormonal factors appear to regulate bile acid synthesis in the rat, no evidence for this was found in human hepatocytes, and this represents a useful model for further studies of the synthesis and regulation of bile acids.
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Analysis of ileal sodium/bile acid cotransporter and related nuclear receptor genes in a family with multiple cases of idiopathic bile acid malabsorption.
Marco Montagnani,Anna Abrahamsson,Cecilia Gälman,Gösta Eggertsen,Hanns-Ulrich Marschall,Elisa Ravaioli,Curt Einarsson,Paul A. Dawson +7 more
TL;DR: In this paper, the analysis of ileal sodium/bile acid cotransporter and related nuclear receptor genes in a family with multiple cases of idiopathic bile acid malabsorption was performed.
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Randomized crossover study in patients with neuroendocrine tumors to assess patient preference for lanreotide Autogel(®) given by either self/partner or a health care professional.
Viktor Johanson,Benedicte Wilson,Anna Abrahamsson,Constantin Jianu,Jan Calissendorff,Najme Wall,Henning Grønbæk,Jon Florholmen,Anders Öhberg,Dan Granberg +9 more
TL;DR: Many patients with neuroendocrine tumors prefer self/partner injection of lanreotide Autogel, and are able to self/ partner inject without any impact on efficacy or safety, and this administration method seems to provide a good alternative for suitable patients to increase patient independence and reduce the number of clinic visits.