Ann Wang
Tsinghua University
4 Papers
Ann Wang is an academic researcher from Tsinghua University. The author has contributed to research in topics: Genome & Chromosome. The author has an hindex of 3, co-authored 4 publications. Previous affiliations of Ann Wang include New York University & Johns Hopkins University School of Medicine.
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Papers
Engineering the ribosomal DNA in a megabase synthetic chromosome
Weimin Zhang,Guanghou Zhao,Guanghou Zhao,Zhouqing Luo,Yicong Lin,Lihui Wang,Yakun Guo,Ann Wang,Shuangying Jiang,Qingwen Jiang,Jianhui Gong,Yun Wang,Sha Hou,Jing Huang,Tianyi Li,Yiran Qin,Junkai Dong,Qin Qin,Jiaying Zhang,Xinzhi Zou,Xi He,Li Zhao,Yibo Xiao,Meng Xu,Erchao Cheng,Ning Huang,Tong Zhou,Yue Shen,Roy Walker,Yisha Luo,Zheng Kuang,Leslie A. Mitchell,Kun Yang,Sarah M. Richardson,Yi Wu,Bing-Zhi Li,Ying-Jin Yuan,Huanming Yang,Jiwei Lin,Guo-Qiang Chen,Qingyu Wu,Joel S. Bader,Yizhi Cai,Jef D. Boeke,Junbiao Dai +44 more
TL;DR: The ability to design, build, and debug a megabase-sized chromosome, together with the flexibility in rDNA locus position, speaks to the remarkable overall flexibility of the yeast genome.
233
Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond
Leslie A. Mitchell,Ann Wang,Ann Wang,Giovanni Stracquadanio,Giovanni Stracquadanio,Giovanni Stracquadanio,Zheng Kuang,Xuya Wang,Kun Yang,Kun Yang,Sarah M. Richardson,J. Andrew Martin,Yu Zhao,Roy Walker,Yisha Luo,Hongjiu Dai,Kang Dong,Zuojian Tang,Yanling Yang,Yizhi Cai,Adriana Heguy,Beatrix Ueberheide,David Fenyö,Junbiao Dai,Joel S. Bader,Joel S. Bader,Jef D. Boeke +26 more
TL;DR: Analyses of phenotypes, transcriptomics, and proteomics of synVI and poly-syn strains reveal, in general, WT cell properties and the existence of rare bugs resulting from genome editing.
224
Denosumab for prevention of fractures in postmenopausal women with osteoporosis. Editorial comment
Cummings,Js Martin,Mccloug,Es Siris,R. Eastell,Ir Reid,Pierre D. Delmas,Hb Zoog,M. Austin,Ann Wang,Stepan Kutilek,Silvano Adami,J.R. Zanchetta,Cesar Libanati,S. Siddhanti,C. Christiansen +15 more
- 01 Jan 2009
TL;DR: It is shown that subcutaneous injections of denosumab every 6 months for 36 months is associated with a significant reduction in the risk of vertebral, hip, and nonvertebral fractures among postmenopausal women with osteoporosis.
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Construction of Comprehensive Dosage-Matching Core Histone Mutant Libraries for Saccharomyces cerevisiae
Shuangying Jiang,Shuangying Jiang,Yan Liu,Ann Wang,Yiran Qin,Maoguo Luo,Qingyu Wu,Jef D. Boeke,Junbiao Dai,Junbiao Dai +9 more
TL;DR: It is shown that addition of a second copy of the mutant histone gene could rescue the lethality in some previously known mutants that cannot survive with a single copy.
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