Ann S.N. Lau
Population Council
7 Papers
22 Citations
Ann S.N. Lau is an academic researcher from Population Council. The author has contributed to research in topics: Adherens junction & Microtubule. The author has an hindex of 6, co-authored 6 publications. Previous affiliations of Ann S.N. Lau include The Chinese University of Hong Kong.
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Papers
Defective CFTR-dependent CREB activation results in impaired spermatogenesis and azoospermia.
Wen Ming Xu,Jing Chen,Hui Chen,Rui Ying Diao,Rui Ying Diao,Kin Lam Fok,Jian Da Dong,Ting Ting Sun,Wen Ying Chen,Wen Ying Chen,Mei Kuen Yu,Xiao Hu Zhang,Lai Ling Tsang,Ann S.N. Lau,Qi Xian Shi,Qinghua Shi,Pingbo Huang,Hsiao Chang Chan +17 more
TL;DR: In this article, the role of CFTR and sAC in regulating the cAMP-CREB signaling pathway in Sertoli cells, defect of which may result in impaired spermatogenesis and azoospermia.
81
RAB13 Participates in Ectoplasmic Specialization Dynamics in the Rat Testis
Dolores D. Mruk,Ann S.N. Lau +1 more
TL;DR: It is demonstrated that RAB13—a guanosine triphosphatase (GTPase) known to participate in tight junction function in other epithelia—also participates in the dynamics of the ectoplasmic specialization, a testis-specific type of anchoring junction.
23
Interprofessional education—situations of a university in Hong Kong and major hurdles to teachers and students
Joyce T. S. Li,Janita Pak Chun Chau,Samuel Y. S. Wong,Ann S.N. Lau,Wallace C. H. Chan,Peggy Yip,Yijian Yang,Fred K.T Ku,Felix Sze,I. King,Vivian W Y Lee +10 more
TL;DR: In this paper , the authors conducted a cross-sectional quantitative study to evaluate the feasibility, acceptance, and educational value of interprofessional education in Hong Kong, and found that despite the positive attitude of university teachers and students toward IPE, barriers that could hinder the development of IPE included heavy teaching and administrative load and logistic arrangement for classroom arrangement and academic scheduling involving multiple faculties.
Rab4A GTPase catenin interactions are involved in cell junction dynamics in the testis.
TL;DR: The ability of Rab4A to associate with alpha- and beta-catenin increased during Adjudin-induced junction restructuring in the testis, illustrating that Rab4a-Catenin interactions are likely to be involved in the disassembly of Sertoli-germ cell contacts.
Role of Tissue Inhibitor of Metalloproteases‐1 in Junction Dynamics in the Testis
TL;DR: During maturation, the steady-state TIMP-1 mRNA level in the testis increased significantly from 40 to 60 days of age, which suggests its role in the restructuring of the epithelium during spermiation and suggests that the assembly of adherens junctions may involve protease inhibitors.