Ann E. Jarrell
Pacific Northwest National Laboratory
5 Papers
125 Citations
Ann E. Jarrell is an academic researcher from Pacific Northwest National Laboratory. The author has contributed to research in topics: Analyte & Bead. The author has an hindex of 5, co-authored 5 publications.
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Papers
Suspension array analysis of 16S rRNA from Fe- and SO(4)2- reducing bacteria in uranium-contaminated sediments undergoing bioremediation.
Darrell P. Chandler,Ann E. Jarrell,Eric R. Roden,Julia Golova,Boris Chernov,Matthew J. Schipma,Aaron D. Peacock,Philip E. Long +7 more
TL;DR: It is concluded that ecologically relevant and meaningful information can be derived from direct microarray analysis of rRNA in uncharacterized environmental samples, even with the current analytical uncertainty surrounding the behavior of individual probes on tunable bead arrays.
Enhanced nucleic acid capture and flow cytometry detection with peptide nucleic acid probes and tunable-surface microparticles.
TL;DR: This study investigated whether tunable-surface bead chemistry and peptide nucleic acids (PNA) could enhance the recovery and detection of intact rRNA in both test tube and automated suspension array hybridization formats.
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Automated Purification and Suspension Array Detection of 16S rRNA from Soil and Sediment Extracts by Using Tunable Surface Microparticles
TL;DR: Tunable surface microparticles were used both as an rRNA affinity purification resin in a renewable microcolumn sample preparation system and as the sensor surface in a flow cytometer detector, which was as efficacious as manual methods for simultaneous sample purification, hybridization, and washing prior to flow cytometry detection.
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Automated sample preparation method for suspension arrays using renewable surface separations with multiplexed flow cytometry fluorescence detection
TL;DR: A new method of automated sample preparation for multiplexed biological analysis systems that use flow cytometry fluorescence detection by trapping color-encoded microspheres temporarily trapped in a renewable surface separation column to enable perfusion with sample and reagents prior to delivery to the detector.
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Taking arrays from the lab to the field: trying to make sense of the unknown
TL;DR: A clear distinction is drawn between hypothesis-driven fundamental science and operational uses of microarray technology and an environmental microbiologist's perspective on technology needs and requirements for quantitatively analyzing microbial communities is offered.
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