Ankit Jain
University of Pennsylvania
13 Papers
21 Citations
Ankit Jain is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Receptor & NMDA receptor. The author has an hindex of 8, co-authored 12 publications. Previous affiliations of Ankit Jain include Brandeis University.
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Papers
Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice
Jesús Planagumà,Frank Leypoldt,Francesco Mannara,Francesco Mannara,Javier Gutiérrez-Cuesta,Elena Martín-García,Esther Aguilar,Maarten J. Titulaer,Mar Petit-Pedrol,Ankit Jain,Rita J. Balice-Gordon,Melike Lakadamyali,Francesc Graus,Rafael Maldonado,Josep Dalmau,Josep Dalmau,Josep Dalmau +16 more
TL;DR: Findings establish a link between memory and behavioural deficits and antibody-mediated reduction of NMDAR, provide the biological basis by which removal of antibodies and antibodies-producing cells improve neurological function, and offer a model for testing experimental therapies in this and similar disorders.
Acute mechanisms underlying antibody effects in anti-N-methyl-D-aspartate receptor encephalitis.
Emilia H. Moscato,Xiaoyu Peng,Ankit Jain,Thomas D. Parsons,Josep Dalmau,Rita J. Balice-Gordon +5 more
TL;DR: Prolonged exposure of hippocampal neurons to antibodies from patients with anti‐NMDAR encephalitis caused a reversible decrease in the synaptic localization and function of NMDARs.
347
A Polymorphism in CALHM1 Influences Ca2+ Homeostasis, Aβ Levels, and Alzheimer's Disease Risk
Ute Dreses-Werringloer,Jean-Charles Lambert,Valérie Vingtdeux,Haitian Zhao,Horia Vais,Adam P. Siebert,Ankit Jain,Jeremy Koppel,Anne Rovelet-Lecrux,Didier Hannequin,Florence Pasquier,Daniela Galimberti,Elio Scarpini,David M. A. Mann,Corinne Lendon,Dominique Campion,Philippe Amouyel,Peter Davies,Peter Davies,J. Kevin Foskett,Fabien Campagne,Philippe Marambaud,Philippe Marambaud +22 more
TL;DR: It is proposed that CALHM1 encodes an essential component of a previously uncharacterized cerebral Ca(2+) channel that controls Abeta levels and susceptibility to late-onset AD.
327
Organelle positioning in muscles requires cooperation between two KASH proteins and microtubules
TL;DR: The KASH proteins Klar and M SP-300 cooperate to promote even myonuclear spacing by linking the MSP-300 nuclear ring to the astral microtubule network.
138
Anti–N-methyl-D-aspartate Receptor Encephalitis During Pregnancy
Monisha A. Kumar,Ankit Jain,Valerie E. Dechant,Tsukasa Saito,Timothy Rafael,Hitoshi Aizawa,Kevin Dysart,Takayuki Katayama,Yasuo Ito,Nobuo Araki,Tatsuya Abe,Rita J. Balice-Gordon,Josep Dalmau +12 more
TL;DR: The current study shows that anti-NMDAR encephalitis during pregnancy can have a good outcome for the mother and newborn.