Anke Leinhaas
University of Bonn
8 Papers
86 Citations
Anke Leinhaas is an academic researcher from University of Bonn. The author has contributed to research in topics: Cellular differentiation & Stem cell. The author has an hindex of 8, co-authored 8 publications.
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Papers
Anticancer Effects of Niclosamide in Human Glioblastoma
Anja Wieland,Daniel Trageser,Sabine Gogolok,Roman Reinartz,Heike Höfer,Mihaela Keller,Anke Leinhaas,Ramona Schelle,Sabine Normann,Lil Klaas,Andreas Waha,Philipp Koch,Rolf Fimmers,Torsten Pietsch,Anthony T. Yachnis,David W. Pincus,Dennis A. Steindler,Oliver Brüstle,Matthias Simon,Martin Glas,Björn Scheffler +20 more
TL;DR: Together, the data advocate the use of pGBMs for exploration of compound libraries to reveal unexpected leads, for example, niclosamide that might be suited for further development toward personalized clinical application.
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Residual tumor cells are unique cellular targets in glioblastoma
Martin Glas,Barbara H. Rath,Matthias Simon,Roman Reinartz,Anja Schramme,Daniel Trageser,Ramona Eisenreich,Anke Leinhaas,Mihaela Keller,Hans-Ulrich Schildhaus,Stephan Garbe,Barbara Steinfarz,Torsten Pietsch,Dennis A. Steindler,Johannes Schramm,Ulrich Herrlinger,Oliver Brüstle,Björn Scheffler +17 more
TL;DR: In vitro analysis of proliferation, invasion, stem cell qualities, GBM‐typical antigens, genotypes, and in vitro drug and irradiation challenge studies revealed residual tumor cells as unique entities.
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Whole-brain 3D mapping of human neural transplant innervation
Jonas Doerr,Martin K. Schwarz,Dirk Wiedermann,Anke Leinhaas,Alina Jakobs,Florian Schloen,Inna Schwarz,Michael Diedenhofen,Nils Christian Braun,Philipp Koch,Daniel A. Peterson,Ulrich Kubitscheck,Mathias Hoehn,Oliver Brüstle +13 more
TL;DR: The findings indicate that transplant connectivity is largely dictated by the circuitry of the target region and depict rabies-based transsynaptic tracing and LSFM as efficient tools for comprehensive assessment of host–donor cell innervation.
Neural conversion of human embryonic stem cell colonies in the presence of fibroblast growth factor-2.
TL;DR: It is suggested that fibroblast growth factor-2 exposure alone suffices to promote neural conversion of adherently growing human embryonic stem cell cultures.
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Stage-specific conditional mutagenesis in mouse embryonic stem cell-derived neural cells and postmitotic neurons by direct delivery of biologically active Cre recombinase.
TL;DR: The ability to conduct Cre/loxP recombination at defined stages of stem cell differentiation in an expression‐independent manner provides new prospects for studying the role of individual genes under stringent temporal control.
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