Angi Dai
3 Papers
Angi Dai is an academic researcher. The author has contributed to research in topics: Internal medicine & Immunology. The author has an hindex of 1, co-authored 1 publications.
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Papers
Early intestinal microbial features are associated with CD4 T cell recovery after allogeneic hematopoietic transplant.
Oriana Miltiadous,Nicholas R. Waters,Hana Andrlova,Angi Dai,Chi L. Nguyen,Marina Burgos da Silva,Sarah Lindner,John B. Slingerland,Paul A Giardina,Annelie Clurman,Gabriel K Armijo,Antonio L.C. Gomes,Madhavi Lakkaraja,Peter Maslak,Michael Scordo,Roni Shouval,Anna Staffas,Richard J. O'Reilly,Ying Taur,Susan E. Prockop,Jaap Jan Boelens,Sergio Giralt,Miguel-Angel Perales,Sean M. Devlin,Jonathan U. Peled,Kate A. Markey,Marcel R.M. van den Brink +26 more
TL;DR: It is observed that increased fecal relative abundance of genus Staphylococcus during the early post-transplant period was associated with worse CD4 T cell recovery, and this suggests that the intestinal bacteria can affect early lymphopoiesis and the homeostasis of allograft-derived T cells after transplantation.
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Immune-related colitis is associated with fecal microbial dysbiosis and can be mitigated by fecal microbiota transplantation.
Arielle Elkrief,Nicholas R. Waters,Natalie Smith,Angi Dai,John B. Slingerland,Nathan Aleynick,Binita Febles,Pooja Gogia,Nicholas D. Socci,Melissa Lumish,Paul A Giardina,Jamie E. Chaft,Juliana Eng,Robert J. Motzer,Robin B. Mendelsohn,Kate A. Markey,Mingqiang Zhuang,Yanyun Li,Zhifan Yang,Travis J. Hollmann,Charles M. Rudin,Marcel Van Den Brink,Jinru Shia,Susan DeWolf,Adam J. Schoenfeld,Matthew D. Hellmann,N. Esther Babady,David Faleck,Jonathan U. Peled +28 more
TL;DR: FMT was followed by clinical improvements in several cases of steroid- and biologic-agent-refractory irColitis, and was followed by clinical improvements in several cases of steroid- and biologic-agent-refractory irColitis.
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Enterococcus induces MHC-II expression by the intestinal epithelium during murine graft-versus-host disease.
Chi L. Nguyen,Jennifer Funes,Romina Ghale,Nathan Duong,Kristen Victor,Brianna Gipson,Zhenrun J Zhang,Angi Dai,Rita Li,Gabe K Armijo,Ashley Huang,Miriam Martinez,Yuqing Chen,D. Ghazarian,Melissa D. Docampo,Khyati V. Pathak,Patrick Pirrotte,Kate A. Markey,Jonathan U. Peled,Jenny Paredes,Marina Burgos da Silva,Marcel R. M. van den Brink +21 more
TL;DR: Enterococcus domination in the gut exacerbates graft-versus-host disease (GVHD) by inducing MHC-II expression in intestinal epithelial cells, leading to increased inflammation and mortality, and targeting this axis may prevent lethal GVHD.