Angela D. Bhalla
University of Texas MD Anderson Cancer Center
11 Papers
67 Citations
Angela D. Bhalla is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Malignant peripheral nerve sheath tumor & Medicine. The author has an hindex of 6, co-authored 10 publications. Previous affiliations of Angela D. Bhalla include University of Texas Health Science Center at Houston & University of Texas at Austin.
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Papers
A UPF3-mediated regulatory switch that maintains RNA surveillance
Wai Kin Chan,Angela D. Bhalla,Angela D. Bhalla,Hervé Le Hir,Lam Son Nguyen,Lulu Huang,Lulu Huang,Jozef Gecz,Jozef Gecz,Miles F. Wilkinson,Miles F. Wilkinson +10 more
TL;DR: UPF3A levels are tightly regulated by a post-transcriptional switch to maintain appropriate levels of NMD substrates in cells containing different levels of UPF3B.
129
Comparison of Cancer Prevalence in Patients With Neurofibromatosis Type 1 at an Academic Cancer Center vs in the General Population From 1985 to 2020.
Jace P. Landry,Kelsey L Schertz,Yi-Ju Chiang,Angela D. Bhalla,Min Yi,Emily Z. Keung,Christopher P. Scally,Barry W. Feig,Kelly K. Hunt,Christina L. Roland,Ashleigh Guadagnolo,Andrew J. Bishop,Alexander J. Lazar,John M. Slopis,Ian E. McCutcheon,Keila E. Torres +15 more
- 01 Mar 2021
TL;DR: In this paper, the authors evaluated the prevalence of neoplasia and outcomes among patients with Neurofibromatosis type 1 (NF1) and found that patients with NF1 developed some neoplasms more frequently and at a younger age compared with individuals without NF1.
Genome-wide association study of maternal and inherited loci for conotruncal heart defects.
A. J. Agopian,Laura E. Mitchell,Joseph T. Glessner,Angela D. Bhalla,Anshuman Sewda,Hakon Hakonarson,Hakon Hakonarson,Elizabeth Goldmuntz,Elizabeth Goldmuntz +8 more
TL;DR: Novel candidate loci for CTDs are suggested, including loci that appear to be associated with the risk of CTDs via the maternal genotype, but further studies are needed to confirm these associations.
Nonsense codons trigger an RNA partitioning shift.
Angela D. Bhalla,Jayathi P. Gudikote,Jun Wang,Wai Kin Chan,Yao Fu Chang,Renee O. Olivas,Miles F. Wilkinson +6 more
TL;DR: Evidence is provided that two responses collaborate to elicit NIPS, and it is proposed that NIPS collaborates with NMD to retain and degrade a subset of PTC+ transcripts at the outer nuclear membrane and/or within the nucleoplasm.
24
Exon sequencing of PAX3 and T (brachyury) in cases with spina bifida.
A. J. Agopian,Angela D. Bhalla,Eric Boerwinkle,Richard H. Finnell,Megan L. Grove,James E. Hixson,Lawrence C. Shimmin,Anshuman Sewda,Colin Stuart,Yu Zhong,Huiping Zhu,Laura E. Mitchell +11 more
TL;DR: These studies provide some evidence that common variants of PAX3 and T are associated with spina bifida, and rare and novel variants in these genes were also identified in affected individuals.