Anes Ju
Max Planck Society
17 Papers
107 Citations
Anes Ju is an academic researcher from Max Planck Society. The author has contributed to research in topics: Glucose tolerance test & Diabetes mellitus. The author has an hindex of 10, co-authored 15 publications. Previous affiliations of Anes Ju include Catholic University of Korea & University of Göttingen.
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Papers
Heterozygous ambra1 deficiency in mice: a genetic trait with autism-like behavior restricted to the female gender.
Ekrem Dere,Liane Dahm,Derek Lu,Kurt Hammerschmidt,Anes Ju,Martesa Tantra,Anne Kästner,Kamal Chowdhury,Hannelore Ehrenreich,Hannelore Ehrenreich +9 more
TL;DR: Surprisingly, comprehensive behavioral characterization of these mice revealed an autism-like phenotype in Ambra1+/− females only, including compromised communication and social interactions, a tendency of enhanced stereotypies/repetitive behaviors, and impaired cognitive flexibility.
Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.
TL;DR: Together, these data support an early manifestation of communication deficits in Nlgn4(-/-) mice that appear more pronounced in immature females with their overall stronger USV as compared to males.
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Expression of serotonin 1A and 2A receptors in molecular- and projection-defined neurons of the mouse insular cortex
TL;DR: A molecular and neuroanatomical map of the 5-HT system within the insular cortex is defined, providing ground knowledge to identify the potential role of serotonergic modulation of selective insular populations in anxiety.
Sexual dimorphism of AMBRA1 -related autistic features in human and mouse
Marina Mitjans,Marina Mitjans,Martin Begemann,Martin Begemann,Anes Ju,Ekrem Dere,Ekrem Dere,Liane Wüstefeld,Sabine Hofer,Imam Hassouna,Johannes Balkenhol,Bárbara Oliveira,S Van der Auwera,Roland Tammer,Kurt Hammerschmidt,Henry Völzke,Georg Homuth,Francesco Cecconi,Kamal Chowdhury,Hans-Jörgen Grabe,Jens Frahm,Susann Boretius,Thomas Dandekar,Hannelore Ehrenreich,Hannelore Ehrenreich +24 more
TL;DR: It is shown in two independent human samples that a single normal AMBRA1 genotype, the intronic SNP rs3802890-AA, is associated with autistic features in women, who also display lower AMBra1 mRNA expression in peripheral blood mononuclear cells relative to female GG carriers, and suggest Ambra1 heterozygous mice as a novel multifaceted and construct-valid genetic mouse model for female autism.
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The effects of alcohol abstinence on BDNF, ghrelin, and leptin secretions in alcohol-dependent patients with glucose intolerance.
TL;DR: Alcohol abstinence might influence diabetes-related factors of alcohol-dependent patients with glucose intolerance and BDNF, ghrelin, and leptin differently affect this improvement, depending on the stage of DM.
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