Ane Korff
University of Washington
16 Papers
50 Citations
Ane Korff is an academic researcher from University of Washington. The author has contributed to research in topics: Medicine & Downregulation and upregulation. The author has an hindex of 11, co-authored 11 publications. Previous affiliations of Ane Korff include North-West University & University of Cape Town.
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Papers
CNS tau efflux via exosomes is likely increased in Parkinson's disease but not in Alzheimer's disease
Min Shi,Andrej Kovac,Andrej Kovac,Andrej Kovac,Ane Korff,Travis J. Cook,Carmen Ginghina,Kristin M. Bullock,Kristin M. Bullock,Li Yang,Tessandra Stewart,Danfeng Zheng,Danfeng Zheng,Patrick Aro,Anzari Atik,Kathleen F. Kerr,Cyrus P. Zabetian,Cyrus P. Zabetian,Elaine R. Peskind,Elaine R. Peskind,Shu Ching Hu,Shu Ching Hu,Joseph F. Quinn,Douglas Galasko,Thomas J. Montine,William A. Banks,William A. Banks,Jing Zhang,Jing Zhang +28 more
TL;DR: Alzheimer's disease and Parkinson's disease involve tau pathology, where Tau is detectable in blood, but its clearance from neuronal cells and the brain is poorly understood.
CSF α-synuclein improves diagnostic and prognostic performance of CSF tau and Aβ in Alzheimer’s disease
TL;DR: Assessment of α-synuclein in cerebrospinal fluid and its association with CSF total tau, phosphorylated tau181, and amyloid beta1-42 in subjects of the Alzheimer’s Disease Neuroimaging Initiative (ADNI) with longitudinal clinical assessments suggests inclusion of measures of CSF α- Syn improves the diagnostic sensitivity/specificity of classic CSF AD biomarkers and better predicts longitudinal cognitive changes.
Diagnostic values of cerebrospinal fluid t-tau and Aβ42 using Meso Scale Discovery assays for Alzheimer’s disease
Catherine Pan,Ane Korff,Douglas Galasko,Carmen Ginghina,Elaine R. Peskind,Ge Li,Joseph F. Quinn,Thomas J. Montine,Kevin C. Cain,Min Shi,Jing Zhang +10 more
TL;DR: Both MSD CSF t-tau and Aβ42 assays demonstrated consistent and stable analytical performance, as well as resistance to several important pre-analytic variables, and candidate diagnostic cut-off values are proposed for the first time.
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Cheek cell-derived α-synuclein and DJ-1 do not differentiate Parkinson's disease from control.
Tessandra Stewart,Yu Ting Sui,Luis F. Gonzalez-Cuyar,David T.W. Wong,David Akin,Vitor Tumas,Jan O. Aasly,Emily Ashmore,Patrick Aro,Carmen Ginghina,Ane Korff,Cyrus P. Zabetian,Cyrus P. Zabetian,James B. Leverenz,James B. Leverenz,Min Shi,Jing Zhang +16 more
TL;DR: Cheek epithelium was identified, which forms the majority of the cellular component of saliva and is readily accessible clinically, as 1 of several potential sources of salivary α-syn and DJ-1, but no PD-related trend was present.
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Evaluating the behavioural consequences of early maternal separation in adult C57BL/6 mice; the importance of time.
TL;DR: Evidence is presented in support of long lasting effects of early MS on adult mouse behaviour, which were only apparent when time was included as a significant dimension of behaviour on the EPM, which could reflect adaptive aspects of stress-driven behaviours in MS mice.
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