Andy L Johnson
University of Oxford
9 Papers
14 Citations
Andy L Johnson is an academic researcher from University of Oxford. The author has contributed to research in topics: Immunological Synapses & Biology. The author has an hindex of 5, co-authored 9 publications. Previous affiliations of Andy L Johnson include National Institutes of Health.
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Papers
Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.
Katrina L. Randall,Katrina L. Randall,Teresa Lambe,Andy L Johnson,Andy L Johnson,Bebhinn Treanor,Edyta M. Kucharska,Heather Domaschenz,Belinda Whittle,Lina E. Tze,Anselm Enders,Tanya L. Crockford,Tiphaine Bouriez-Jones,Duncan Alston,Jason G. Cyster,Michael J. Lenardo,Fabienne Mackay,Elissa K. Deenick,Stuart G. Tangye,Tyani D. Chan,Tahra Camidge,Robert Brink,Carola G. Vinuesa,Facundo D. Batista,Richard J. Cornall,Christopher C. Goodnow +25 more
TL;DR: Humoral immunodeficiency due to Dock8 mutation provides evidence that organization of the immunological synapse is critical for signaling the survival of B cell subsets required for long-lasting immunity.
DOCK8 is essential for T‐cell survival and the maintenance of CD8+ T‐cell memory
Teresa Lambe,Greg Crawford,Andy L Johnson,Tanya L. Crockford,Tiphaine Bouriez-Jones,Aisling M. Smyth,Trung H.M. Pham,Qian Zhang,Alexandra F. Freeman,Jason G. Cyster,Helen C. Su,Richard J. Cornall +11 more
TL;DR: Findings help to explain why DOCK8‐deficient patients are susceptible to recurrent infections and provide new insights into how T‐cell memory is sustained.
Erratum: Corrigendum: Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection
Andy L Johnson,L. Aravind,Natalia Shulzhenko,Andre Morgun,Seeyoung Choi,Tanya L. Crockford,Teresa Lambe,Heather Domaschenz,Edyta M. Kucharska,Lixin Zheng,Carola G. Vinuesa,Michael J. Lenardo,Christopher C. Goodnow,Richard J. Cornall,Ronald H. Schwartz +14 more
TL;DR: In the version of this article initially published, the top right graph in Figure 7b is incorrect, and the error has been corrected in the HTML and PDF versions of the article.
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Normobaric hypoxia elevates free fatty acids and impairs cardiac energetics and diastolic function in normal human volunteers
Cameron J. Holloway,Lowri E. Cochlin,Ion Codreanu,Edward Bloch,Marzieh Fatemianl,Cezary Szmigielski,Andy L Johnson,Jane M Francis,Peter A. Robbins,Stefan Neubauer,Kieran Clarke +10 more
TL;DR: Cardiac function was measured using magnetic resonance imaging (MRI) and echocardiography, and high-energy phosphate metabolism was measured as the ratio of phosphocreatine to ATP (PCr/ATP) by 31Phosphorus magnetic resonance spectroscopy before and after twenty hours of hypoxia.
Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production (vol 10, pg 1283, 2009)
Katrina L. Randall,Teresa Lambe,Andy L Johnson,Bebhinn Treanor,Edyta M. Kucharska,Heather Domaschenz,Belinda Whittle,Lina E. Tze,Anselm Enders,Tanya L. Crockford,Tiphaine Bouriez-Jones,Duncan Alston,Jason G. Cyster,Michael J. Lenardo,Fabienne Mackay,Elissa K. Deenick,Stuart G. Tangye,Tyani D. Chan,Tahra Camidge,Robert Brink,Carola G. Vinuesa,Facundo D. Batista,Richard J. Cornall,Christopher C. Goodnow +23 more
TL;DR: Corrigendum: Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.