Andrew Williams
University of Pennsylvania
6 Papers
1 Citations
Andrew Williams is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Mitophagy & Neuropsychology. The author has an hindex of 4, co-authored 5 publications.
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Papers
Cognitive and Pathological Influences of Tau Pathology in Lewy Body Disorders
David G. Coughlin,Sharon X. Xie,Mendy Liang,Andrew Williams,Claire Peterson,Daniel Weintraub,Daniel Weintraub,Corey T. McMillan,David A. Wolk,Rizwan S. Akhtar,Howard I. Hurtig,H. Branch Coslett,Roy H. Hamilton,Andrew Siderowf,John E. Duda,John E. Duda,Katya Rascovsky,Edward B. Lee,Virginia M.-Y. Lee,Murray Grossman,John Q. Trojanowski,David J. Irwin +21 more
TL;DR: Using digital histology in a large autopsy cohort of Lewy body disorder patients with dementia to test the hypotheses that co‐occurring Alzheimer disease pathology impacts the anatomic distribution of α‐synuclein (SYN) pathology and that co-occurring neocortical tau pathology in LBDs associates with worse cognitive performance and occurs in a pattern differing from AD.
Dysregulated mitophagy and mitochondrial transport in severe dominant optic atrophy due to OPA1 mutations
C Liao,Neil Ashley,Karl J. Morten,Kanchan Phadwal,Andrew Williams,Ian M. Fearnley,L Rosser,J Lowndes,Carl Fratter,David J. P. Ferguson,Laura Vay,Gerardine Quaghebeur,L Macleod,A. Gabriel,Susan M. Downes,K. Simon,Marcela Votruba,Joanna Poulton +17 more
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Mp12-14 rural disparities in penile cancer: a multi-institutional, statewide review in west virginia
David Zekan,Luke P. O'Connor,M. Novak,Amr Elbakry,Brian Wiseman,Ahmad Haffar,Andrew Williams,Nathan Hale,Adam Luchey,Ali Hajiran +9 more
TL;DR: Men in minority groups were less likely to undergo pre prostate biopsy mpMRI compared to men in majority groups as discussed by the authors , and men in the South and West were more likely to have prostate cancer.
Occupational attainment influences longitudinal decline in behavioral variant frontotemporal degeneration.
Lauren Massimo,Sharon X. Xie,Lior Rennert,Donna M. Fick,Amy Halpin,Katerina Placek,Andrew Williams,Katya Rascovsky,David J. Irwin,Murray Grossman,Corey T. McMillan +10 more
TL;DR: The longitudinal findings suggest that bvFTD individuals with higher lifetime cognitive experience demonstrate more rapid decline on measures of executive function, and this finding converges with cross-sectional evidence suggesting that lifetime cognitive experiences contribute to heterogeneity in clinical progression in bv FTD.
Divergent patterns of TDP-43 and tau pathologies in primary progressive aphasia.
Lucia A. A. Giannini,Lucia A. A. Giannini,Sharon X. Xie,Corey T. McMillan,Mendy Liang,Andrew Williams,Charles Jester,Katya Rascovsky,David A. Wolk,Sharon Ash,Edward B. Lee,John Q. Trojanowski,Murray Grossman,David J. Irwin +13 more
TL;DR: To measure postmortem burden of frontotemporal lobar degeneration with TDP‐43 (FTLD‐TDP) or tau (FT LD‐Tau) proteinopathy across hemispheres in primary progressive aphasia (PPA) using digital histopathology and to identify clinicopathological correlates of these distinct proteinopathies.