Andrew Shih
The Feinstein Institute for Medical Research
16 Papers
18 Citations
Andrew Shih is an academic researcher from The Feinstein Institute for Medical Research. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 5, co-authored 16 publications.
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Papers
Identification of grade and origin specific cell populations in serous epithelial ovarian cancer by single cell RNA-seq.
Andrew Shih,A.W. Menzin,J.S. Whyte,J.L. Lovecchio,Anthony Liew,Houman Khalili,Tawfiqul Bhuiya,Peter K. Gregersen,Peter K. Gregersen,Annette Lee,Annette Lee +10 more
TL;DR: Differential gene expression shows myeloid lineage cells are the primary cell group expressing soluble factors in primary samples while fibroblasts do so in metastatic samples, and the proportion of these populations changes from primary to metastatic in a shift from mainly epithelial cells to leukocytes with few cancer epithelium cells in the metastases.
Analysis of menstrual effluent: diagnostic potential for endometriosis
Laura A. Warren,Andrew Shih,Susana Marquez Renteira,Tamer Seckin,Brandon Blau,Kim R. Simpfendorfer,Kim R. Simpfendorfer,Annette Lee,Annette Lee,Christine N. Metz,Christine N. Metz,Peter K. Gregersen +11 more
TL;DR: Menstrual effluent can be useful for investigating the pathobiology of endometriosis and for developing a non-invasive diagnostic for endometiosis which may lead to earlier and more effective treatments for this common disorder.
Autoimmune Disease–Associated Haplotypes of BLK Exhibit Lowered Thresholds for B Cell Activation and Expansion of Ig Class‐Switched B Cells
Kim R. Simpfendorfer,Brandon E. Armstead,Andrew Shih,Wentian Li,Mark Curran,Nataly Manjarrez-Orduño,Annette Lee,Betty Diamond,Peter K. Gregersen +8 more
TL;DR: This study characterized the BLK risk haplotype and determined associated B cell functional phenotypes involved in autoimmunity to characterize the mechanisms by which reduced expression alters human B cell function to confer autoimmune disease susceptibility.
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Menstrual Effluent Provides a Novel Diagnostic Window on the Pathogenesis of Endometriosis
Ashima Nayyar,Matthew I. Saleem,Matthew I. Saleem,Mine Yilmaz,Margaret DeFranco,Gila Klein,Kristine Mae Elmaliki,Elena Kowalsky,Prodyot K. Chatterjee,Xiangying Xue,Radhika Viswanathan,Andrew Shih,Peter K. Gregersen,Peter K. Gregersen,Christine N. Metz,Christine N. Metz +15 more
- 22 Jul 2020
TL;DR: Analysis of menstrual effluent-derived stromal fibroblast cells from women with and without endometriosis can provide an accurate, rapid, and non-invasive diagnostic for endometRIosis and insight into disease pathogenesis.
Arg206Cys substitution in DNASE1L3 causes a defect in DNASE1L3 protein secretion that confers risk of systemic lupus erythematosus.
Latanya N Coke,Hongxiu Wen,Mary E. Comeau,Mustafa H. Ghanem,Andrew Shih,Christine N. Metz,Wentian Li,Carl D. Langefeld,Peter K. Gregersen,Kim R. Simpfendorfer +9 more
TL;DR: In this paper, the effect of the Arg206Cys sequence change on DNASE1L3 protein function was examined in the case of systemic lupus erythematosus (SLE).
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