Andrew M. Rupert
Cincinnati Children's Hospital Medical Center
4 Papers
Andrew M. Rupert is an academic researcher from Cincinnati Children's Hospital Medical Center. The author has contributed to research in topics: Biology & Biobank. The author has an hindex of 4, co-authored 4 publications. Previous affiliations of Andrew M. Rupert include University of Cincinnati.
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Papers
Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease
Leah C. Kottyan,Leah C. Kottyan,Benjamin P. Davis,Joseph D. Sherrill,Kan Liu,Mark Rochman,Kenneth M. Kaufman,Kenneth M. Kaufman,Matthew T. Weirauch,Samuel E. Vaughn,Sara Lazaro,Sara Lazaro,Andrew M. Rupert,Mojtaba Kohram,Emily M. Stucke,Katherine A. Kemme,Albert F. Magnusen,Albert F. Magnusen,Hua He,Phillip Dexheimer,Mirna Chehade,Robert A. Wood,Robbie D. Pesek,Brian P. Vickery,David Fleischer,Robert Lindbad,Hugh A. Sampson,Vincent A. Mukkada,Phil E. Putnam,J. Pablo Abonia,Lisa J. Martin,John B. Harley,John B. Harley,Marc E. Rothenberg +33 more
TL;DR: A model to explain the tissue-specific nature of EoE that involves the interplay of allergic sensitization with an Eosinophilic esophagitis-specific, IL-13–inducible esophageal response involving CAPN14 is proposed.
The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
Leah C. Kottyan,Erin E. Zoller,Jessica Bene,Xiaoming Lu,Jennifer A. Kelly,Andrew M. Rupert,Christopher J. Lessard,Samuel E. Vaughn,Miranda C. Marion,Matthew T. Weirauch,Bahram Namjou,Adam Adler,Astrid Rasmussen,Stuart B. Glenn,Courtney G. Montgomery,Gideon M. Hirschfield,Gang Xie,Catalina Coltescu,Christopher I. Amos,He Li,John A. Ice,Swapan K. Nath,Xavier Mariette,Simon J Bowman,Maureen Rischmueller,Susan C. Lester,Johan G. Brun,Lasse G. Gøransson,Erna Harboe,Roald Omdal,Deborah S. Cunninghame-Graham,Timothy J. Vyse,Corinne Miceli-Richard,Michael T. Brennan,James A. Lessard,Marie Wahren-Herlenius,Marika Kvarnström,Gabor G. Illei,Torsten Witte,Roland Jonsson,Per Eriksson,Gunnel Nordmark,Wan-Fai Ng,Juan-Manuel Anaya,Nelson L. Rhodus,Barbara M. Segal,Joan T. Merrill,Judith A. James,Joel M. Guthridge,R. Hal Scofield,Marta E. Alarcón-Riquelme,Sang Cheol Bae,Susan A. Boackle,Lindsey A. Criswell,Gary S. Gilkeson,Diane L. Kamen,Chaim O. Jacob,Robert P. Kimberly,Elizabeth E. Brown,Jeffrey C. Edberg,Graciela S. Alarcón,John D. Reveille,Luis M. Vilá,Michelle Petri,Rosalind Ramsey-Goldman,Barry I. Freedman,Timothy B. Niewold,Anne M. Stevens,Betty P. Tsao,Jun Ying,Maureen D. Mayes,Olga Y. Gorlova,Ward Wakeland,Timothy R D J Radstake,E. Martin,Javier Martin,Katherine A. Siminovitch,Kathy L. Sivils,Patrick M. Gaffney,Carl D. Langefeld,John B. Harley,Kenneth M. Kaufman +81 more
TL;DR: Both SLE elements of the statistical model appear to operate in Sjögren's syndrome and systemic sclerosis whereas only the IRF5-TNPO3 gene-spanning haplotype is associated with primary biliary cirrhosis, demonstrating the nuance of similarity and difference in autoimmune disease risk mechanisms at IRF 5- TNPO3.
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The Genomics Research and Innovation Network: creating an interoperable, federated, genomics learning system.
Kenneth D. Mandl,Kenneth D. Mandl,Tracy A. Glauser,Tracy A. Glauser,Ian D. Krantz,Ian D. Krantz,Paul Avillach,Paul Avillach,Anna Bartels,Alan H. Beggs,Alan H. Beggs,Sawona Biswas,Florence T. Bourgeois,Florence T. Bourgeois,Jeremy J. Corsmo,Jeremy J. Corsmo,Andrew Dauber,Batsal Devkota,Gary R. Fleisher,Gary R. Fleisher,Allison Heath,Ingo Helbig,Ingo Helbig,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,Judson Kilbourn,Sek Won Kong,Sek Won Kong,Susan Kornetsky,Joseph A. Majzoub,Joseph A. Majzoub,Keith Marsolo,Lisa J. Martin,Lisa J. Martin,Jeremy Nix,Amy Schwarzhoff,Jason Stedman,Arnold W. Strauss,Arnold W. Strauss,Kristen L. Sund,Deanne Taylor,Deanne Taylor,Peter White,Peter White,Eric D. Marsh,Adda Grimberg,Colin P. Hawkes,Darlene Barkman,Erin M. Borglund,Ramkrishna Chakrabarty,Alka Chandel,Anil Kumar Degala,Anil Kumar Degala,Thomas N DeSain,Philip Dexheimer,Parth Divekar,Alyssa Ellis,Mike Furgason,Mike Furgason,Christopher Geehan,Andrew Joseph Guidetti,Alba Gutierrez,Barbara Hallinan,Barbara Hallinan,Becca Harper,Niloofar Jalali,Jaspreet Khanna,Jaspreet Khanna,Christopher P. Kirby,Gabor Korodi,Michal Kouril,Amy Kratchman,Ranjay Kumar,Guillaume Labilloy,In-Hee Lee,Bria Morgan,James Morgan,Louis J. Muglia,Louis J. Muglia,Aleksandr Nikitin,Aleksandr Nikitin,Mike Pistone,Anna Poduri,Andrew M. Rupert,Kristen Safier,Piotr Sliz,Gelvina Stevenson,Joseph W. St. Geme,Vidhu V Thaker,Vidhu V Thaker,Simone Temporal,Prakash Velayutham,Julie Wijesooriya,Bryan A. Wolf,Andrew Wooten,Alan Yen,Yu Zhang +97 more
TL;DR: The GRIN collaboration establishes the technology, policy, and procedures for a scalable genomic research network, across sites of care, and begins to successfully utilize the infrastructure for grant applications.
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The struggle to find reliable results in exome sequencing data: filtering out Mendelian errors.
Zubin Patel,Zubin Patel,Leah C. Kottyan,Leah C. Kottyan,Sara Lazaro,Sara Lazaro,Marc S. Williams,David H. Ledbetter,Gerard Tromp,Andrew M. Rupert,Mojtaba Kohram,Michael Wagner,Ammar Husami,Yaping Qian,C. Alexander Valencia,Kejian Zhang,Margaret K. Hostetter,John B. Harley,John B. Harley,Kenneth M. Kaufman,Kenneth M. Kaufman +20 more
TL;DR: The data cleaning process improves the signal to noise ratio in terms of variants and facilitates the identification of candidate disease causative polymorphisms.