Andrew L. Hook
University of Nottingham
82 Papers
504 Citations
Andrew L. Hook is an academic researcher from University of Nottingham. The author has contributed to research in topics: Chemistry & Biofilm. The author has an hindex of 27, co-authored 74 publications. Previous affiliations of Andrew L. Hook include Flinders University & Commonwealth Scientific and Industrial Research Organisation.
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Papers
Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells
Ying Mei,Krishanu Saha,Said R. Bogatyrev,Jing Yang,Andrew L. Hook,Z. Ilke Kalcioglu,Seung Woo Cho,Maisam Mitalipova,Neena Pyzocha,Fredrick Rojas,Krystyn J. Van Vliet,Martyn C. Davies,Morgan R. Alexander,Robert Langer,Rudolf Jaenisch,Daniel G. Anderson +15 more
TL;DR: In this article, the authors identify the optimal substrates within a range of different polymeric surfaces to support the growth and self-renewal of human embryonic stem cells from fully dissociated single cells.
Combinatorial Development of Biomaterials for Clonal Growth of Human Pluripotent Stem Cells
Ying Mei,Krishanu Saha,Said R. Bogatyrev,Jing Yang,Andrew L. Hook,Z. Ilke Kalcioglu,Seung Woo Cho,Maisam Mitalipova,Neena Pyzocha,Fredrick Rojas,Krystyn J. Van Vliet,Martyn C. Davies,Morgan R. Alexander,Robert Langer,Rudolf Jaenisch,Daniel G. Anderson +15 more
- 01 Aug 2010
TL;DR: These analyses show that optimal hES cell substrates are generated from monomers with high acrylate content, have a moderate wettability, and employ integrin αvβ3 and αv β5 engagement with adsorbed vitronectin to promote colony formation.
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Combinatorial discovery of polymers resistant to bacterial attachment
Andrew L. Hook,Chien-Yi Chang,Jing Yang,Jeni Luckett,Alan Cockayne,Steve Atkinson,Ying Mei,Roger Bayston,Derek J. Irvine,Robert Langer,Daniel G. Anderson,Paul Williams,Martyn C. Davies,Morgan R. Alexander +13 more
TL;DR: Hook et al. as discussed by the authors presented a high-throughput method to find materials that resist bacterial attachment and colonization, which is problematic for medical devices, such as pacemakers.
High throughput methods applied in biomaterial development and discovery
Andrew L. Hook,Daniel G. Anderson,Robert Langer,Paul Williams,Martyn C. Davies,Morgan R. Alexander +5 more
TL;DR: The literature in this area is reviewed and it is concluded that for polymers this process is best achieved in a microarray format, which enable thousands of cell-material interactions to be monitored on a single chip.
250
Biomaterial modification of urinary catheters with antimicrobials to give long-term broadspectrum antibiofilm activity
Leanne E. Fisher,Andrew L. Hook,Waheed Ashraf,Anfal Yousef,David A. Barrett,David J. Scurr,Xinyong Chen,Emily F. Smith,Michael W. Fay,Christopher D. J. Parmenter,Richard Parkinson,Roger Bayston +11 more
TL;DR: The antimicrobial catheter offers for the first time a means of reducing infection and its complications in long-term urinary catheter users.
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