Andrew Cluster
Washington University in St. Louis
8 Papers
34 Citations
Andrew Cluster is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Myeloid leukemia & Stem cell. The author has an hindex of 4, co-authored 8 publications.
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Papers
Unrelated Umbilical Cord Blood Transplantation for Sickle Cell Disease Following Reduced-Intensity Conditioning: Results of a Phase I Trial
Allistair Abraham,Andrew Cluster,David A. Jacobsohn,David Delgado,Monica L. Hulbert,Divyesh Kukadiya,Lisa Murray,Shalini Shenoy +7 more
TL;DR: The addition of thiotepa to a previously tested reduced-intensity conditioning (RIC) regimen was able to achieve donor engraftment in the majority of patients and future efforts will focus on further reducing rates of acute GVHD and viral infection.
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Pten Cell Autonomously Modulates the Hematopoietic Stem Cell Response to Inflammatory Cytokines
Shaina N. Porter,Andrew Cluster,Robert A.J. Signer,Jenna Voigtmann,Darlene Monlish,Laura G. Schuettpelz,Jeffrey A. Magee +6 more
TL;DR: Pten regulates HSC mobilization and expansion in the spleen primarily via cell-autonomous mechanisms and modulates the HSC response to inflammatory cytokines.
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Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy
Ran Chen,Theresa Okeyo-Owuor,Riddhi M Patel,Emily B. Casey,Andrew Cluster,Wei Yang,Jeffrey A. Magee +6 more
TL;DR: In this paper, the myeloid tumor suppressor KMT2C deletions convey a selective advantage to hematopoietic stem cells (HSCs) after chemotherapy treatment that may precipitate t-MDS/t-AML.
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Haploidentical BMT Using Fully Myeloablative Conditioning, T Cell Replete Bone Marrow Grafts, and Post-Transplant Cyclophosphamide (PT/Cy) Has Limited Toxicity and Promising Efficacy in the First Prospective Multicenter Trial for Pediatric, Adolescent, and Young Adult Patients with High Risk Acute Leukemias and Myelodysplastic Syndrome
Heather J. Symons,Andrew Cluster,Emi Caywood,Jignesh Dalal,R. Maarten Egeler,Jeffrey S. Huo,Michelle Hudspeth,Amy K. Keating,Susan Kelly,Joerg Krueger,Dean A. Lee,Leslie Lehmann,Lisa Madden,Benjamin R. Oshrine,Heather Schneider,Kirk R. Schultz,Michael A. Pulsipher,Terry J. Fry +17 more
TL;DR: In this article, the first prospective multicenter pilot trial in the Pediatric Blood and Marrow Transplant Consortium (PBMTC) for high risk acute leukemias and myelodysplastic syndrome (MDS) was reported.
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