Andrés Jaso
University of Navarra
15 Papers
366 Citations
Andrés Jaso is an academic researcher from University of Navarra. The author has contributed to research in topics: Quinoxaline & Chemical synthesis. The author has an hindex of 11, co-authored 15 publications.
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Papers
Synthesis of new quinoxaline-2-carboxylate 1,4-dioxide derivatives as anti-Mycobacterium tuberculosis agents.
TL;DR: The potency, selectivity, and low cytotoxicity of these compounds make them valid leads for synthesizing new compounds that possess better activity, including activity in macrophages.
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Synthesis and antimycobacterial activity of new quinoxaline-2-carboxamide 1,4-di-N-oxide derivatives.
TL;DR: Results indicate that compounds with a methyl moiety substituted in position 3 and unsubstituted benzyl substituted on the carboxamide group provide an efficient approach for further development of anti-tuberculosis agents.
139
Synthesis of new 2-acetyl and 2-benzoyl quinoxaline 1,4-di-N-oxide derivatives as anti-Mycobacterium tuberculosis agents.
TL;DR: The potency, selectivity and low cytotoxicity of 2-acetyl-3-methylquinoxaline 1,4-di-N-oxide derivatives make them valid leads for synthesizing new compounds that possess better activity.
114
Quinoxaline N,N′-dioxide derivatives and related compounds as growth inhibitors of Trypanosoma cruzi. Structure–activity relationships
Gabriela Aguirre,Hugo Cerecetto,Rossanna Di Maio,Mercedes González,Marı́a Elena Montoya Alfaro,Andrés Jaso,Belén Zarranz,M. A. Ortega,Ignacio Aldana,Antonio Monge-Vega +9 more
TL;DR: Quinoxaline derivatives presented good inhibitor activity of growth of Trypanosoma cruzi in in vitro assays and a multiple correlation between activity and lipophilic properties and LUMO energy was established.
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Synthesis of New 2-Acetyl and 2-Benzoyl Quinoxaline 1,4-Di-N-oxide Derivatives as anti-Mycobacterium tuberculosis Agents.
TL;DR: A series of 2-acetyl and 2-benzoyl-6(7)-substituted quinoxaline 1,4-di-Noxide derivatives were synthesized and evaluated for in vitro antituberculosis activity.
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