Andreas Sundgren
University of Gothenburg
11 Papers
99 Citations
Andreas Sundgren is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Tetrasaccharide & Ether. The author has an hindex of 7, co-authored 11 publications. Previous affiliations of Andreas Sundgren include Stockholm University.
Chat about Author
Papers
Design and synthesis of multifunctional gold nanoparticles bearing tumor-associated glycopeptide antigens as potential cancer vaccines.
Raymond P. Brinãs,Andreas Sundgren,Padmini Sahoo,Susan Morey,Kate Rittenhouse-Olson,Greg E. Wilding,Wei Deng,Joseph J. Barchi +7 more
TL;DR: The synthesis of a novel vaccine construction prepared from spherical gold nanoparticles of 3-5 nm core diameters showed a small but statistically significant immune response with production of both IgM and IgG isotypes and suggested that this platform may be a viable delivery system for tumor-associated glycopeptide antigens.
115
Identification of the smallest structure capable of evoking opsonophagocytic antibodies against Streptococcus pneumoniae type 14.
Dodi Safari,Huberta A. Th. Dekker,John A. F. Joosten,Dirk Michalik,Adriana Carvalho de Souza,Roberto Adamo,Martina Lahmann,Andreas Sundgren,Stefan Oscarson,Stefan Oscarson,Johannis P. Kamerling,Harm Snippe +11 more
TL;DR: The broader study described here, which evaluated 16 oligosaccharides, showed that the branched trisaccharide element Glc-(Gal-)GlcNAc is essential in inducing Pn14PS-specific antibodies and that the neighboring galactose unit at the nonreducing end contributes clearly to the immunogenicity of the epitope.
107
Varied presentation of the Thomsen-Friedenreich disaccharide tumor-associated carbohydrate antigen on gold nanoparticles.
TL;DR: Three-dimensional self-assembled monolayers of gold coated with the Thomsen-Friedenreich antigen disaccharide in a variety of presentations should prove extremely useful in exploring the binding properties and immune response to this important carbohydrate antigen.
49
Synthesis of oligosaccharides corresponding to Vibrio cholerae O139 polysaccharide structures containing dideoxy sugars and a cyclic phosphate
TL;DR: A spacer-equipped tetrasaccharide, p-aminocyclohexylethyl alpha-l-Colp-1-->2)-beta-d-Galp-(1-->3)-[alpha- l- Colp-( 1-->4)]-beta-D-GlcpNAc, containing a 4,6-cyclic phosphate in the galactose residue, has been synthesised.
32
Block Synthesis of Streptococcus pneumoniae Type 14 Capsular Polysaccharide Structures
TL;DR: Synthesis of a thioglycoside tetrasaccharide block, corresponding to the repeating unit of Streptococcus pneumoniae serotype 14 CPS, yields an octa and a dodecasaccharides derivative ready for conjugation to proteins to afford immunoactive glycoconjugates.
27