Andreas Schmid
University of Miami
29 Papers
72 Citations
Andreas Schmid is an academic researcher from University of Miami. The author has contributed to research in topics: Medicine & Mucociliary clearance. The author has an hindex of 16, co-authored 27 publications. Previous affiliations of Andreas Schmid include University of Basel.
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Papers
Soluble adenylyl cyclase is localized to cilia and contributes to ciliary beat frequency regulation via production of cAMP.
Andreas Schmid,Zoltan Sutto,Marie Christine Nlend,Gabor Horvath,Nathalie Schmid,Jochen Buck,Lonny R. Levin,Gregory E. Conner,Nevis Fregien,Matthias Salathe +9 more
TL;DR: CO2/HCO3 − increases indeed reversibly stimulate intracellular cAMP production by sAC in intact cells, and it contributes to the regulation of human airway CBF.
Decreased Soluble Adenylyl Cyclase Activity in Cystic Fibrosis Is Related to Defective Apical Bicarbonate Exchange and Affects Ciliary Beat Frequency Regulation
Andreas Schmid,Zoltan Sutto,Zoltan Sutto,Nathalie Schmid,Lisa Novak,Pedro I. Ivonnet,Gabor Horvath,Gabor Horvath,Gregory E. Conner,Nevis Fregien,Matthias Salathe +10 more
TL;DR: The results suggest that CBF regulation by sAC-produced cAMP could be impaired in CF, thereby possibly contributing to mucociliary dysfunction in this disease, at least during disease exacerbations when airway acidification is common.
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Modulation of Wnt signaling is essential for the differentiation of ciliated epithelial cells in human airways.
TL;DR: Findings indicate that enhanced β‐catenin signaling decreases the number of ciliated cells and causes squamous changes in the epithelium, whereas treatment with DDk1 leads to an increased number ofciliated cells.
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The Clinical Features of Bronchiectasis Associated with Alpha-1 Antitrypsin Deficiency, Common Variable Immunodeficiency and Primary Ciliary Dyskinesia--Results from the U.S. Bronchiectasis Research Registry.
Edward Eden,Radmila Choate,Alan F. Barker,Doreen Addrizzo-Harris,Timothy R. Aksamit,Charles L. Daley,M. Leigh Anne Daniels,Angela DiMango,Kevin P. Fennelly,David E. Griffith,Margaret M. Johnson,Michael R. Knowles,Mark L. Metersky,Peadar G. Noone,Anne E. O'Donnell,Kenneth N. Olivier,Matthias Salathe,Andreas Schmid,Byron Thomashow,Gregory Tino,Gerard M. Turino,Kevin L. Winthrop +21 more
TL;DR: The group with PCD had more symptoms, greater morbidity, lower lung function and more commonly were infected by Pseudomonas aeruginosa compared to other groups, and a greater proportion of them reported having exacerbations and/or hospitalizations in the past 2 years.
Airway Clearance Techniques in Bronchiectasis: Analysis from the United States Bronchiectasis and Non-TB Mycobacteria Research Registry
Ashwin Basavaraj,Radmila Choate,Doreen Addrizzo-Harris,Timothy R. Aksamit,Alan F. Barker,Charles L. Daley,M. Leigh Anne Daniels,Edward Eden,Angela DiMango,Kevin P. Fennelly,David E. Griffith,Margaret M. Johnson,Michael R. Knowles,Mark L. Metersky,Peadar G. Noone,Anne E. O'Donnell,Kenneth N. Olivier,Matthias Salathe,Andreas Schmid,Byron Thomashow,Gregory Tino,Kevin L. Winthrop +21 more
TL;DR: In this paper, the authors used unadjusted and adjusted multinomial logistic regression models to assess the relationship between airway clearance techniques and clinical outcomes in patients with bronchiectasis and a productive cough.
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