Andreas Pelz
Charité
10 Papers
2 Citations
Andreas Pelz is an academic researcher from Charité. The author has contributed to research in topics: Biology & Antibody. The author has an hindex of 5, co-authored 7 publications. Previous affiliations of Andreas Pelz include Leibniz Association & Humboldt University of Berlin.
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Papers
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
Frank Szulzewsky,Andreas Pelz,Xi Feng,Michael Synowitz,Darko Markovic,Thomas Langmann,Inge R. Holtman,Xi Wang,Bart J. L. Eggen,Hendrikus Boddeke,Dolores Hambardzumyan,Susanne A. Wolf,Helmut Kettenmann +12 more
TL;DR: It is demonstrated that the expression of Gpnmb and Spp1 is highly upregulated in both murine and human glioma-associated microglia/macrophage phenotype including a mixture of M1 and M2a,b,c-specific genes.
Minocycline rescues decrease in neurogenesis, increase in microglia cytokines and deficits in sensorimotor gating in an animal model of schizophrenia.
Daniele Mattei,Anais Djodari-Irani,Ravit Hadar,Andreas Pelz,Lourdes Fernandez de Cossío,Thomas Goetz,Marina Matyash,Helmut Kettenmann,Christine Winter,Susanne A. Wolf +9 more
TL;DR: These findings strongly support the idea to use anti-inflammatory drugs to target microglia activation as an adjunctive therapy in schizophrenic patients.
Selective depletion of plasma cells in vivo based on the specificity of their secreted antibodies
Qingyu Cheng,Qingyu Cheng,Andreas Pelz,Andreas Pelz,Adriano Taddeo,Laleh Khodadadi,Laleh Khodadadi,Jens Klotsche,Bimba F. Hoyer,Bimba F. Hoyer,Tobias Alexander,Tobias Alexander,Andreas Thiel,Gerd-R. Burmester,Andreas Radbruch,Falk Hiepe,Falk Hiepe +16 more
TL;DR: First‐time use of an antigen‐antibody (OVA/anti‐CD138 antibody) conjugate for in vivo labeling and selective ablation of plasma cells that secrete antibodies specific for the antigen OVA should enable the development of unique causative treatment strategies for established antibody‐mediated diseases sparing humoral immunity.
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Opposite Regulation of Homer Signal at the NMJ Postsynaptic Micro Domain between Slow- and Fast-Twitch Muscles in an Experimentally Induced Autoimmune Myasthenia Gravis (EAMG) Mouse Model
Martin Schubert,Andreas Pelz,G. Trautmann,Katharina Block,Sandra Furlan,Martina Gutsmann,Siegfried Kohler,Pompeo Volpe,Dieter Blottner,Andreas Meisel,Michele Salanova +10 more
TL;DR: In this article , an experimentally induced autoimmune model of Myasthenia Gravis (EAMG) and correlated to motor end plate integrity was used to investigate the role of Homer in skeletal muscle neurophysiology, showing that postsynaptic Homer signalling is impaired in slow-twitch SOL muscle from EAMG mice.
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Corrigendum to “Minocycline rescues decrease in neurogenesis, increase in microglia cytokines and deficits in sensorimotor gating in an animal model of schizophrenia” [Brain Behav. Immun. 38 (2014) 175–184]
Daniele Mattei,Anais Djodari-Irani,Ravit Hadar,Andreas Pelz,Lourdes Fernandez de Cossío,Thomas Goetz,Marina Matyash,Helmut Kettenmann,Christine Winter,Susanne A. Wolf +9 more
TL;DR: As a result of a mistake in software handling of the StereoInvestigator software, the wrong parameters were used to calculate microglia density based on Iba1–DAB reactivity and the results were shown in the right scale with the correct unit (cells/mm) and the correct significance level (p < 0.05).
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