Andreas M. Zeiher
Goethe University Frankfurt
606 Papers
7.5K Citations
Andreas M. Zeiher is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Medicine & Myocardial infarction. The author has an hindex of 129, co-authored 571 publications. Previous affiliations of Andreas M. Zeiher include University of Hamburg.
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Papers
Transcoronary Concentration Gradient of microRNA-133a and Outcome in Patients With Coronary Artery Disease.
Roberta De Rosa,Salvatore De Rosa,David M. Leistner,Jes-Niels Boeckel,Till Keller,Stephan Fichtlscherer,Stefanie Dimmeler,Andreas M. Zeiher +7 more
TL;DR: The release of miR133a, as measured by its transcoronary concentration gradient, is associated with a higher incidence of MACE in patients with CAD, but it does not add significant prognostic information compared with traditional prognostic biomarkers, therefore limiting its potential usefulness in the clinical practice.
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Atherogenesis—recent insights into basic mechanisms and their clinical impact
TL;DR: In this paper, an important mechanical endothelial stimulus mediated by shear stress due to increased blood flow: the flowdependent dilation of precapillary resistance as well as conductance vessels allows blood flow to increase according to metabolic demand.
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Platelet reactivity and clinical outcomes in acute coronary syndrome patients treated with prasugrel and clopidogrel: a pre-specified exploratory analysis from the TROPICAL-ACS trial.
Daniel Aradi,Lisa Gross,Dietmar Trenk,Tobias Geisler,Béla Merkely,Róbert Gábor Kiss,András Komócsi,Csaba András Dézsi,Zoltán Ruzsa,Imre Ungi,Konstantinos D. Rizas,Andreas E. May,Andreas Mügge,Andreas M. Zeiher,Lesca M. Holdt,Kurt Huber,Franz-Josef Neumann,Lukasz Koltowski,Zenon Huczek,Martin Hadamitzky,Steffen Massberg,Dirk Sibbing +21 more
TL;DR: Based on this substudy of a randomized trial, selecting prasugrel or clopidogrel based on PFT resulted in similar ischaemic outcomes as uniform prasUGrel therapy without HPR.
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High glucose reduces cathepsin L activity and impairs invasion of circulating progenitor cells
TL;DR: High glucose significantly reduces the protein expression and activity of cathepsin L, which is involved in matrix degradation and required for invasion of EPC into the ischemic tissue, and, thereby, may limit the functional capacity of E PC to improve neovascularization in diabetics.
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A human cell atlas of the pressure-induced hypertrophic heart
Luka Nicin,S. M. Schroeter,Simone F. Glaser,Ralf Schulze-Brüning,Minh Duc Pham,Susanne Hille,Michail Yekelchyk,Badder Kattih,Wesley Abplanalp,Lukas Tombor,Oliver J. Müller,Thomas Braun,Benjamin Meder,Christoph Reich,Mani Arsalan,Tomas Holubec,Thomas Walther,Fabian Emrich,Jaya Krishnan,Andreas M. Zeiher,David John,Stefanie Dimmeler +21 more
TL;DR: In this paper , the transcriptional response of human cardiomyocytes to pressure overload caused by aortic valve stenosis and major alterations in cardiac cellular crosstalk was described.