Andreas Lackner
Medical University of Vienna
32 Papers
228 Citations
Andreas Lackner is an academic researcher from Medical University of Vienna. The author has contributed to research in topics: Biology & Cell cycle. The author has an hindex of 13, co-authored 27 publications.
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Papers
Deregulation of the activin/follistatin system in hepatocarcinogenesis.
Michael Grusch,Claudia Drucker,Barbara Peter-Vörösmarty,Natascha Erlach,Andreas Lackner,Annemarie Losert,Doris Macheiner,Wolfgang J. Schneider,Marcela Hermann,Nigel P. Groome,Wolfram Parzefall,Walter Berger,Bettina Grasl-Kraupp,Rolf Schulte-Hermann +13 more
TL;DR: The sensitivity of preneoplastic hepatocytes to activin signals suggests the activin/follistatin system as promising target for therapeutic intervention and the balanced expression of follistatins and activins becomes deregulated during hepatocarcinogenesis.
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In vitro anti-cancer activity of two ethno-pharmacological healing plants from Guatemala Pluchea odorata and Phlebodium decumanum.
Manuela Gridling,Nicole Stark,Sibylle Madlener,Andreas Lackner,Ruxandra Popescu,Birgit Benedek,Rene Diaz,Foster M. Tut,Thanh Phuong Nha Vo,Daniela Huber,Michaela Gollinger,Philipp Saiko,Ali Özmen,Wilhelm Mosgoeller,Rainer de Martin,Ruth Eytner,Karl-Heinz Wagner,Michael Grusch,Monika Fritzer-Szekeres,Thomas Szekeres,Brigitte Kopp,Richard Frisch,Georg Krupitza +22 more
TL;DR: The anti-neoplastic potential of two healing plants used by the Maya of the Guatemala/Belize area against severe inflammatory conditions such as neuritis, rheumatism, arthritis, coughs, bruises and tumours is demonstrated.
MSX2 safeguards syncytiotrophoblast fate of human trophoblast stem cells.
Ruth Hornbachner,Andreas Lackner,Henrieta Papuchova,Sandra Haider,Martin Knöfler,Karl Mechtler,Paulina A. Latos +6 more
TL;DR: In this article, msh homeobox 2 (MSX2) was found to be a key transcriptional regulator of trophoblast identity using the human trophoballast stem cell model.
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Synergistic effects of erlotinib and everolimus on bronchial carcinoids and large-cell neuroendocrine carcinomas with activated EGFR/AKT/mTOR pathway.
Zsuzsanna Bago-Horvath,Wolfgang Sieghart,Michael Grusch,Andreas Lackner,Hubert Hayden,Christine Pirker,Oxana Komina,Józefa Węsierska-Gądek,Andrea Haitel,Martin Filipits,Walter Berger,Katharina Schmid +11 more
TL;DR: This study indicates that EGFR and mTOR are clinically important targets in bronchial neuroendocrine tumors, and further in vivo and clinical exploration of combined inhibition is warranted.
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Suppression of activin A signals inhibits growth of malignant pleural mesothelioma cells
MA Hoda,J Münzker,Bahil Ghanim,Karin Schelch,Thomas Klikovits,Viktoria Laszlo,Emine Sahin,A Bedeir,Andreas Lackner,Balazs Dome,Ulrike Setinek,Martin Filipits,Maria Eisenbauer,István Kenessey,Szilvia Török,Tamás Garay,Balazs Hegedus,A Catania,S. Taghavi,Walter Klepetko,Walter Berger,Michael Grusch +21 more
TL;DR: This study suggests that activin A contributes to the malignant phenotype of MPM cells via regulation of cyclin D and may represent a valuable candidate for therapeutic interference.