Andreas Hofmann
Heidelberg University
21 Papers
82 Citations
Andreas Hofmann is an academic researcher from Heidelberg University. The author has contributed to research in topics: Biology & DNA damage. The author has an hindex of 9, co-authored 17 publications.
Chat about Author
Papers
Self-organised segregation of bacterial chromosomal origins
TL;DR: It is proposed that a non-trivial feedback between the self-organising gradient of MukBEF complexes and the oris leads to accurate ori positioning, and it is shown that oris exhibit biased motion towards MukBEf clusters, rather than mid-cell.
38
Using Persistent Homology as a New Approach for Super-Resolution Localization Microscopy Data Analysis and Classification of γH2AX Foci/Clusters
TL;DR: A new approach to analyze repair foci by their topology is demonstrated in order to obtain a cell independent method of categorization and it is shown that the topology of clusters of γH2AX foci can be categorized depending on the distance to heterochromatin.
37
A topological similarity measure for proteins.
TL;DR: A new measure for assessing similarity among chemical structures, based on well-established computational-topology algorithms, is introduced, which is more than a mere geometric similarity measure, as it takes into account, on different geometric scales, the important topological features of the compared structures.
33
Surface orientation dependent band alignment for CuInSe2–ZnSe–ZnO
TL;DR: In this paper, the interface formation and band-lineup between ZnO and epitaxial CuInSe2 substrates were investigated with photoelectron spectroscopy. And they found a weak dependence of the interfacial dipole on orientation.
27
Elucidation of the Clustered Nano-Architecture of Radiation-Induced DNA Damage Sites and Surrounding Chromatin in Cancer Cells: A Single Molecule Localization Microscopy Approach.
Michael Hausmann,Martin Falk,Charlotte Neitzel,Andreas Hofmann,Abin Biswas,Theresa Gier,Iva Falková,Dieter W. Heermann,Georg Hildenbrand +8 more
TL;DR: In this article, the relationship between the nano-architecture of radiation-induced repair foci (IRIFs), represented here by γH2AX foci, and their chromatin environment was investigated using super-resolution single molecule localization microscopy.
19