Andreas Boland
University of Geneva
24 Papers
2 Citations
Andreas Boland is an academic researcher from University of Geneva. The author has contributed to research in topics: Chemistry & Biology. The author has an hindex of 12, co-authored 19 publications. Previous affiliations of Andreas Boland include Laboratory of Molecular Biology & Max Planck Society.
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Papers
A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing.
Ying Chen,Andreas Boland,Duygu Kuzuoğlu-Öztürk,Praveen Bawankar,Belinda Loh,Chung Te Chang,Oliver Weichenrieder,Elisa Izaurralde +7 more
TL;DR: The structural basis for the repressive activity of CCR4-NOT and its interaction with TNRC6/GW182s is elucidated, and the crystal structure of this complex demonstrates striking similarity to the eIF4G-eIF4A complex.
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A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation.
Joerg E. Braun,Vincent Truffault,Andreas Boland,Eric Huntzinger,Chung Te Chang,Gabrielle Haas,Gabrielle Haas,Oliver Weichenrieder,Murray Coles,Elisa Izaurralde +9 more
TL;DR: It is shown that XRN1 directly interacts with EDC4 and DCP1 in human and Drosophila melanogaster cells, respectively, and provides a molecular basis for the coupling of decapping to 5′→3′ mRNA degradation.
185
Fast native-SAD phasing for routine macromolecular structure determination.
Tobias Weinert,Vincent Olieric,Sandro Waltersperger,Ezequiel Panepucci,Lirong Chen,Hua Zhang,Dayong Zhou,John Rose,Akio Ebihara,Seiki Kuramitsu,Dianfan Li,Nicole Howe,Gisela Schnapp,Alexander Pautsch,Katja Bargsten,Andrea E. Prota,Parag Surana,Jithesh Kottur,Deepak T. Nair,Federica Basilico,Valentina Cecatiello,Sebastiano Pasqualato,Andreas Boland,Oliver Weichenrieder,Bi-Cheng Wang,Michel O. Steinmetz,Martin Caffrey,Meitian Wang +27 more
TL;DR: A data collection method that uses a single crystal to solve X-ray structures by native SAD (single-wavelength anomalous diffraction) and solved the structures of 11 real-life examples, including a human membrane protein, a protein-DNA complex and a 266-kDa multiprotein-ligand complex.
132
Structure and assembly of the NOT module of the human CCR4–NOT complex
Andreas Boland,Ying Chen,Tobias Raisch,Stefanie Jonas,Duygu Kuzuoğlu-Öztürk,Lara Wohlbold,Oliver Weichenrieder,Elisa Izaurralde +7 more
TL;DR: The crystal structure of the human NOT module formed by the CNOT1, CNOT2 and CNOT3 C-terminal (-C) regions is reported, which provides a structural framework for understanding the recruitment of the CCR4–NOT complex to mRNA targets.
122
Structural basis of human separase regulation by securin and CDK1–cyclin B1
Jun Yu,Pierre Raia,Chloe M. Ghent,Tobias Raisch,Yashar Sadian,Simone Cavadini,Pramod M Sabale,David Barford,Stefan Raunser,David O. Morgan,Andreas Boland +10 more
TL;DR: In this article, the authors used cryogenic electron microscopy to determine the structures of separase in complex with either securin or CDK1-cyclin B1-CKS1.
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