Andrea Rinaldi
University of Lugano
96 Papers
429 Citations
Andrea Rinaldi is an academic researcher from University of Lugano. The author has contributed to research in topics: Diffuse large B-cell lymphoma & Gene. The author has an hindex of 34, co-authored 96 publications. Previous affiliations of Andrea Rinaldi include University of Padua.
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Papers
IL-1α secreted by subcapsular sinus macrophages promotes melanoma metastasis in the sentinel lymph node by upregulating STAT3 signaling in the tumor.
Tommaso Virgilio,Joy Bordini,Giulio Sartori,Irene Latino,Daniel Molina-Romero,Cristina Leoni,Murodzhon Akhmedov,Andrea Rinaldi,Alberto J. Arribas,Diego Morone,S. Morteza Seyed Jafari,Marina Bersudsky,Aner Ottolenghi,Ivo Kwee,Anna Maria Chiaravalli,Fausto Sessa,Robert E. Hunger,Antonino Bruno,Lorenzo Mortara,Elena Voronov,Silvia Monticelli,Ron N. Apte,Francesco Bertoni,Santiago F. Gonzalez +23 more
TL;DR: In this paper, the authors characterized the innate inflammatory responses to melanoma metastasis in the sentinel lymph node (sLN) and identified STAT3 as one of the main targets of IL-1α signaling in metastatic cells.
Chromosome 11q23.1 is an unstable region in B-cell tumor cell lines
Giulia Poretti,Ivo Kwee,Barbara Bernasconi,Paola M.V. Rancoita,Andrea Rinaldi,Carlo Capella,Emanuele Zucca,Antonino Neri,Maria Grazia Tibiletti,Francesco Bertoni +9 more
TL;DR: The cytogenetic and molecular characterization of an amplification affecting 11q23.1 in four cell lines derived from B-cell lymphoid tumors is presented and it is possible that 11Q23 amplification might mainly represent the effect of unstable chromosome region.
Genome-wide DNA profiling better defines the prognosis of chronic lymphocytic leukaemia.
Andrea Rinaldi,Michael Mian,Ivo Kwee,Davide Rossi,Clara Deambrogi,Afua Adjeiwaa Mensah,Francesco Forconi,Valeria Spina,Emanuele Cencini,Daniela Drandi,Marco Ladetto,Rita Santachiara,Roberto Marasca,Valter Gattei,Franco Cavalli,Emanuele Zucca,Gianluca Gaidano,Francesco Bertoni +17 more
TL;DR: The prediction of outcome for CLL patients might be improved by evaluating the presence of gains at 2p and 8q as novel genomic regions besides those included in the ‘standard’ fluorescence in situ hybridization panel.
Hairy cell leukemias with unmutated IGHV genes define the minor subset refractory to single-agent cladribine and with more aggressive behavior.
Francesco Forconi,Elisa Sozzi,Emanuele Cencini,Francesco Zaja,Tamara Intermesoli,Caterina Stelitano,Luigi Rigacci,Filippo Gherlinzoni,Renato Cantaffa,Anna Baraldi,Andrea Gallamini,Alfonso Zaccaria,Alessandro Pulsoni,Marco Gobbi,Maristella Tassi,Donatella Raspadori,Lorenzo Leoncini,Andrea Rinaldi,Elena Sabattini,Francesco Bertoni,Stefano Pileri,Francesco Lauria +21 more
TL;DR: The data suggest that UM-HCLs identify the minor subgroup failing cladribine treatment and with more aggressive disease, and new molecular elements relevant for treatment concerns in HCL are provided.
Genomic and expression profiling identifies the B‐cell associated tyrosine kinase Syk as a possible therapeutic target in mantle cell lymphoma
Andrea Rinaldi,Ivo Kwee,M. Taborelli,Cristina Largo,Silvia Uccella,Vittoria Martin,Giulia Poretti,Gianluca Gaidano,Giuseppe Calabrese,Giovanni Martinelli,Luca Baldini,Giancarlo Pruneri,Carlo Capella,Emanuele Zucca,Finbarr E. Cotter,Juan C. Cigudosa,Carlo V. Catapano,Maria Grazia Tibiletti,Francesco Bertoni +18 more
TL;DR: A combination of genomic and expression profiling suggested Syk inhibition as a new therapeutic strategy to be explored in lymphomas.