André Aubry
Centre national de la recherche scientifique
122 Papers
1.6K Citations
André Aubry is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Hydrogen bond & Amide. The author has an hindex of 31, co-authored 122 publications. Previous affiliations of André Aubry include University of Lorraine.
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Papers
Structures of peptides from alpha-amino acids methylated at the alpha-carbon.
Claudio Toniolo,Marco Crisma,Fernando Formaggio,G. Valle,Giorgio Cavicchioni,Gilles Precigoux,André Aubry,Johan Kamphuis +7 more
Abstract: The structural preferences of peptides (and depsipeptides) from the achiral MeAib and Hib residues, and the chiral Iva, (alpha Me) Val, (alpha Me) Leu, and (alpha Me) Phe residues, as determined by conformational energy computations, x-ray diffraction analyses, and 1H-nmr and spectroscopic studies, are reviewed and compared with literature data on Aib-containing peptides. The results obtained indicate that helical structures are preferentially adopted by peptides rich in these alpha-amino acids methylated at the alpha-carbon. Intriguing experimental findings on the impact of the chirality of Iva, (alpha Me) Val, and (alpha Me) Phe residues on helix screw sense are illustrated.
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Crystal Structures of a Poplar Thioredoxin Peroxidase that Exhibits the Structure of Glutathione Peroxidases: Insights into Redox-driven Conformational Changes.
Cha San Koh,Claude Didierjean,Nicolas Navrot,Santosh Panjikar,Guillermo Mulliert,Nicolas Rouhier,Jean-Pierre Jacquot,André Aubry,Omar bin Shawkataly,Catherine Corbier +9 more
TL;DR: The crystal structures of the reduced and oxidized form of Populus trichocarpaxdeltoides GPX5 (PtGPX5) are determined, using a selenomethionine derivative, and it is shown that a drastic conformational change is necessary to bring the two distant cysteine residues together to form an intramolecular disulfide bond.
106
Apo and holo crystal structures of an nadp-dependent aldehyde dehydrogenase from streptococcus mutans
TL;DR: This work solved by molecular replacement the first structure of an NADP-dependent ALDH isolated from Streptococcus mutans, in its apo form and holo form in complex with NADP, at 1.8 and 2.6 A resolution.
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