Anders Elmgren
Sahlgrenska University Hospital
15 Papers
95 Citations
Anders Elmgren is an academic researcher from Sahlgrenska University Hospital. The author has contributed to research in topics: Point mutation & Biology. The author has an hindex of 10, co-authored 15 publications. Previous affiliations of Anders Elmgren include University of Gothenburg.
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Papers
Evolution of fucosyltransferase genes in vertebrates.
Marieta Costache,Marieta Costache,Pol-André Apoil,Anne Cailleau,Anders Elmgren,Göran Larson,Stephen Henry,Antoine Blancher,Dana Iordachescu,Rafael Oriol,Rosella Mollicone +10 more
TL;DR: The results suggest that the fucosyltransferase genes have evolved by successive duplications, followed by translocations, and divergent evolution from a single ancestral gene.
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Point Mutations and Deletion Responsible for the Bombay H null and the Reunion H weak Blood Groups
Pilar Fernandez-Mateos,Anne Cailleau,Stephen Henry,Marieta Costache,Anders Elmgren,Lola Svensson,Göran Larson,Bo E. Samuelsson,Rafael Oriol,Rosella Mollicone +9 more
TL;DR: Single prevalent FUT1 and FUT2 point mutations and a deletion are responsible for the Indian Bombay H null and the Reunion H weak phenotypes found on Reunion island.
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Significance of Individual Point Mutations, T202C and C314T, in the Human Lewis (FUT3) Gene for Expression of Lewis Antigens by the Human α(1,3/1,4)-Fucosyltransferase, Fuc-TIII
Anders Elmgren,Rosella Mollicone,Marieta Costache,Cecilia Börjeson,Rafael Oriol,Joan Harrington,Göran Larson +6 more
TL;DR: It is demonstrated, that the Trp68 → Arg substitution in human Fuc-TIII is the capital amino acid change responsible for the appearance of the Le(a−b−) phenotype on human erythrocytes in individuals homozygous for both the T202C and C314T mutations.
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Determination of Lewis FUT3 gene mutations by PCR using sequence-specific primers enables efficient genotyping of clinical samples.
Ammi Grahn,Anders Elmgren,Lena Åberg,Lola Svensson,Per-Anders Jansson,Peter Lönnroth,Göran Larson +6 more
TL;DR: A polymerase chain reaction method using sequence‐specific primers (PCR‐SSP) for rapid and correct genotyping of the common Lewis (FUT3) gene mutations 59T>G, 202T>C, 314C>T, 508G>A, and 1067T>A is developed.
Typing for the Human Lewis Blood Group System by Quantitative Fluorescence-Activated Flow Cytometry: Large Differences in Antigen Presentation on Erythrocytes between A1, A2, B, O Phenotypes
TL;DR: The flow cytometric technique revealed large differences in staining intensities, within each ABO Le(a–b+) subgroup which was not directly correlated to plasma donation frequencies nor to Secretor or Lewis genotypes.
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