Ana Sofia Cachaço
Instituto Português de Oncologia Francisco Gentil
6 Papers
154 Citations
Ana Sofia Cachaço is an academic researcher from Instituto Português de Oncologia Francisco Gentil. The author has contributed to research in topics: Integrin & Myogenesis. The author has an hindex of 5, co-authored 6 publications. Previous affiliations of Ana Sofia Cachaço include Instituto Gulbenkian de Ciência & University of Lisbon.
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Papers
The extracellular matrix dimension of skeletal muscle development
Sólveig Thorsteinsdóttir,Marianne Deries,Ana Sofia Cachaço,Ana Sofia Cachaço,Fernanda Bajanca +4 more
TL;DR: It is concluded that cell-ECM interactions play significant roles during all stages of skeletal muscle development in the embryo and this "extracellular matrix dimension" should be added to the conceptual network of factors contributing to skeletal myogenesis.
160
Characterization and clinical relevance of circulating and biopsy-derived endothelial progenitor cells in lymphoma patients
Cátia Igreja,Margarida Courinha,Ana Sofia Cachaço,Teresa Pereira,José Cabeçadas,Maria Gomes da Silva,Sergio Dias +6 more
TL;DR: The research has demonstrated the clinical and biological relevance of studying CEPC and LN-EPC in lymphoma patients and revealed the expression of pro-angiogenic and tumor growth factors that may influence lymphoma growth.
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Integrin repertoire on myogenic cells changes during the course of primary myogenesis in the mouse.
Ana Sofia Cachaço,Carlos Silva Pereira,Carlos Silva Pereira,Rita G. Pardal,Fernanda Bajanca,Fernanda Bajanca,Sólveig Thorsteinsdóttir,Sólveig Thorsteinsdóttir +7 more
TL;DR: Myogenic cells change their integrin expression pattern during the course of primary myogenesis in the mouse, suggesting different roles for fibronectin‐ and laminin‐containing matrices in this process.
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TNF-α Regulates the Effects of Irradiation in the Mouse Bone Marrow Microenvironment
Ana Sofia Cachaço,Tânia Carvalho,Ana C. Santos,Cátia Igreja,Rita Fragoso,Catarina Osorio,Manuela Ferreira,Jacinta Serpa,Sofia Correia,Perpétua Pinto-do-Ó,Sergio Dias,Sergio Dias +11 more
TL;DR: It is shown that TNF-α is induced by irradiation and regulates BM cells apoptosis in vitro and in vivo and is a crucial event in BM dysfunction, secondary MDS onset and progression.
Knock-in of integrin β1D affects primary but not secondary myogenesis in mice
Ana Sofia Cachaço,Susana M. Chuva de Sousa Lopes,Ingrid Kuikman,Fernanda Bajanca,Kuniya Abe,Christian Baudoin,Christian Baudoin,Arnoud Sonnenberg,Christine L. Mummery,Sólveig Thorsteinsdóttir +9 more
TL;DR: These results demonstrate for the first time distinct roles for β 1 integrins in primary versus secondary myogenesis and that the β 1A and β1D variants are not functionally equivalent in this process.