An Chi
University of Virginia
12 Papers
85 Citations
An Chi is an academic researcher from University of Virginia. The author has contributed to research in topics: Phosphorylation & Electron-transfer dissociation. The author has an hindex of 11, co-authored 12 publications. Previous affiliations of An Chi include University of Chile.
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Papers
Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry
An Chi,Curtis Huttenhower,Lewis Y. Geer,Joshua J. Coon,Joshua J. Coon,John E. P. Syka,John E. P. Syka,Dina L. Bai,Jeffrey Shabanowitz,Daniel J. Burke,Olga G. Troyanskaya,Donald F. Hunt +11 more
TL;DR: It is shown that phosphoproteins have a higher number of interactions than an average protein and interact with each other more than with a random protein, and are likely to be conserved across large evolutionary distances.
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The utility of ETD mass spectrometry in proteomic analysis.
Leann M. Mikesh,Beatrix Ueberheide,An Chi,Joshua J. Coon,John Edward Philip Syka,John Edward Philip Syka,Jeffrey Shabanowitz,Donald F. Hunt +7 more
TL;DR: The utility of electron transfer dissociation (ETD) mass spectrometry for sequence analysis of post-translationally modified and/or highly basic peptides is reviewed to illustrate the utility of ETD as an advantageous tool in proteomic research by readily identifying peptides resistant to analysis by CAD.
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Genomics, metagenomics and proteomics in biomining microorganisms
Lissette Valenzuela,An Chi,Simon Beard,Alvaro Orell,Nicolas Guiliani,Jeff Shabanowitz,Donald F. Hunt,Carlos A. Jerez +7 more
TL;DR: These powerful approaches are reviewed here since they offer the possibility of exciting new findings that will allow analyzing the community as a microbial system, determining the extent to which each of the individual participants contributes to the process, how they evolve in time to keep the conglomerate healthy and therefore efficient during the entire process of bioleaching.
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Periplasmic Proteins of the Extremophile Acidithiobacillus ferrooxidans A High Throughput Proteomics Analysis
An Chi,Lissette Valenzuela,Simon Beard,Aaron J. Mackey,Jeffrey Shabanowitz,Donald F. Hunt,Carlos A. Jerez +6 more
TL;DR: In this paper, a high-resolution linear ion trap-FT MS was used to identify a total of 131 proteins in the periplasm of acidiobacillus ferrooxidans grown in thiosulfate.
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Sorting of Pmel17 to melanosomes through the plasma membrane by AP1 and AP2: evidence for the polarized nature of melanocytes
Julio C. Valencia,Hidenori Watabe,An Chi,Francois Rouzaud,Kevin G. Chen,Wilfred D. Vieira,Kaoruko Takahashi,Yuji Yamaguchi,Werner Berens,Kunio Nagashima,Jeffrey Shabanowitz,Donald F. Hunt,Ettore Appella,Vincent J. Hearing +13 more
TL;DR: Results show that Pmel17 is sorted to melanosomes by various intracellular routes, directly or indirectly through the plasma membrane, and the presence of basolateral elements in melanocytes suggests their polarized nature.
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