Disclosed are compositions exhibiting a combination of immediate release and controlled release characteristics. The compositions comprise at least one poorly soluble active ingredient having a nanoparticulate particle size, at least one surface stabilizer adsorbed onto the surface of the nanoparticulate active agent particles, and at least one active ingredient having a microparticulate particle size.

Compositions having a combination of immediate release and controlled release characteristics

Skin care compositions disclosed herein include, at a minimum, safe and effective amounts of at least one wrinkle reduction agent, which is a hexapeptide, and a natural exfoliating complex. The skin care compositions provide natural skin exfoliation, reduce fine lines and wrinkles, and improve skin elasticity and firmness.

Skin care compositions including hexapeptide complexes and methods of their manufacture

The present invention is directed to nanoparticulate compositions comprising glipizide. The glipizide particles of the composition preferably have an effective average particle size of less than about 2 microns.

Novel glipizide compositions

The present invention is directed to nanoparticulate active agent compositions comprising lysozyme as a surface stabilizer. Also encompassed by the invention are pharmaceutical compositions comprising a nanoparticulate active agent composition of the invention and methods of making and using such nanoparticulate and pharmaceutical compositions.

Nanoparticulate compositions having lysozyme as a surface stabilizer

This invention relates to stable aminosterol phosphate compositions. The aminosterol phosphate compositions permit administration without associated tissue damage and achieve a sustained release effect.

Formulations comprising aminosterols

Nanoparticulate compositions comprising at least one poorly soluble angiogenesis inhibitor and at least one surface stabilizer are described. The nanoparticulate compositions have an average particle size of less than about 2000 nm. The invention also describes methods of making and using such compositions.

Nanoparticulate compositions of angiogenesis inhibitors

Nanopartikelzusammensetzungen von angiogeneseinhibitoren

La presente invention concerne des compositions nanoparticulaires comprenant au moins un inhibiteur d'angiogenese faiblement soluble et au moins un stabilisateur de surface. Lesdites compositions nanoparticulaires presentent une granulometrie moyenne inferieure a environ 2000 nm. L'invention concerne egalement des methodes de fabrication et d'utilisation desdites compositions.

Compositions nanoparticulaires d'inhibiteurs d'angiogenese

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Nanoparticulate compositions of angiogenesis inhibitors

Nanopartikelzusammensetzungen von angiogeneseinhibitoren

Compositions nanoparticulaires d'inhibiteurs d'angiogenese