Amrit S Gonugunta
University of Texas Southwestern Medical Center
12 Papers
Amrit S Gonugunta is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Medicine & Internal medicine. The author has co-authored 2 publications.
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Papers
Divergent prognostic effects of pre-existing and treatment-emergent thyroid dysfunction in patients treated with immune checkpoint inhibitors
Mitchell S. von Itzstein,Amrit S Gonugunta,Yiqing Wang,Thomas Sheffield,Rong Lu,Sadia Ali,Farjana J. Fattah,Donglu Xie,Jianfeng Cai,Yang Xie,David E. Gerber +10 more
TL;DR: In this article , the authors determined the association between thyroid function and overall survival using Kaplan-Meier curves, log-rank tests, and multivariate Cox proportional hazards model, and found that immunotherapy-induced thyroid dysfunction is associated with better survival, but preexisting thyroid abnormalities convey worse outcomes.
Association between Antibiotic Exposure and Systemic Immune Parameters in Cancer Patients Receiving Checkpoint Inhibitor Therapy
Mitchell S. von Itzstein,Amrit S Gonugunta,Thomas Sheffield,Jade Homsi,Jonathan E. Dowell,Andrew Y. Koh,Prithvi Raj,Farjana J. Fattah,Yiqing Wang,Vijay S. Basava,Shaheen Khan,Jason Y. Park,Vinita Popat,Jessica Saltarski,Yvonne Gloria-McCutchen,David Hsiehchen,Jared Ostmeyer,Yangyi Xie,Quan Zhen Li,Edward K. Wakeland,David E. Gerber +20 more
TL;DR: Antibiotic administration is associated with worse clinical outcomes and changes to the gut microbiome in cancer patients receiving immune checkpoint inhibitors (ICI), and understanding the relationship between these factors may improve the clinical management of patients receiving ICI.
Clinician Variation in Ordering and Completion of Low-Dose Computed Tomography for Lung Cancer Screening in a Safety-Net Medical System.
David E. Gerber,Heidi A. Hamann,Olivia Dorsey,Chul Ahn,Jessica L. Phillips,Noel O. Santini,Travis Browning,Cristhiaan D. Ochoa,Joyce Adesina,Vijaya Subbu Natchimuthu,Eric Steen,Harris Majeed,Amrit S Gonugunta,Simon J. Craddock Lee +13 more
TL;DR: In an integrated safety-net healthcare system, most adult primary care providers order LDCT, and the number of LDCT ordered varies widely among clinicians, and a substantial proportion of ordered LDCT are not completed.
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Pseudoprogression in advanced non-small cell lung cancer treated with combination chemoimmunotherapy: a case report
TL;DR: Pseudoprogression, the initial apparent worsening of cancer prior to eventual improvement, is a documented feature of immune checkpoint inhibitor administration and presents a challenge to clinicians distinguishing true progression from pseudoprogressive as discussed by the authors .
Antibiotic Prescriptions in Lung Cancer and Melanoma Populations: Differences With Potential Clinical Implications in the Immunotherapy Era.
Amrit S Gonugunta,Mitchell S. von Itzstein,David Hsiehchen,Tri Le,Sawsan Rashdan,Hui Yang,C. Selby,Carlos E. Alvarez,David E. Gerber +8 more
TL;DR: In this paper , the authors performed a retrospective cohort study of adults in the U.S. Veterans Affairs (VA) medical system diagnosed with lung cancer or melanoma from 2003 to 2016.
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