Amnah Siddiqa
University of the Sciences
27 Papers
55 Citations
Amnah Siddiqa is an academic researcher from University of the Sciences. The author has contributed to research in topics: Cancer & Insulin resistance. The author has an hindex of 7, co-authored 24 publications. Previous affiliations of Amnah Siddiqa include National University of Sciences and Technology & Maastricht University.
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Papers
Tryptophan catabolism reflects disease activity in human tuberculosis
Jeffrey M. Collins,Amnah Siddiqa,Dean P. Jones,Ken Liu,Russell R. Kempker,Azhar Nizam,N Sarita Shah,Nazir Ahmed Ismail,Nazir Ahmed Ismail,Nazir Ahmed Ismail,Samuel Gurrion Ouma,Nestani Tukvadze,Shuzhao Li,Cheryl L. Day,Cheryl L. Day,Jyothi Rengarajan,Jyothi Rengarajan,James C.M. Brust,Neel R. Gandhi,Joel D. Ernst,Henry M. Blumberg,Thomas R. Ziegler,Thomas R. Ziegler +22 more
TL;DR: Data indicate IDO-1-mediated tryptophan catabolism is highly preserved in the human response to Mycobacterium tuberculosis and could be a target for biomarker development as well as host-directed therapies.
Visualizing the regulatory role of Angiopoietin-like protein 8 (ANGPTL8) in glucose and lipid metabolic pathways
Amnah Siddiqa,Amnah Siddiqa,Elisa Cirillo,Samar H. K. Tareen,Amjad Ali,Martina Kutmon,Lars M. T. Eijssen,Jamil Ahmad,Chris T. Evelo,Susan L. Coort +9 more
TL;DR: To the best of the knowledge, this is the first attempt to present an integrated pathway view of ANGPTL8's regulation and its associated pathways and is important resource for future omics-based studies.
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On the modeling and analysis of the biological regulatory network of NF-{\kappa }B activation in HIV-1 infection
Zurah Bibi,Jamil Ahmad,Amjad Ali,Amnah Siddiqa,Shaheen Shahzad,Samar H. K. Tareen,Hussnain Ahmed Janjua,Shah Khusro +7 more
TL;DR: The hybrid model reveals various viability constraints that characterize the conditional existence of cyclic states (homeostasis) that suggest larger cycle period of HIV-1 than the cycle periods of the other two entities to maintain a homeostatic expressions of these entities.
A new hybrid agent-based modeling & simulation decision support system for breast cancer data analysis
Amnah Siddiqa,M. A. Niaz,Farah Mustafa,Habib Bokhari,Amir Hussain,Noreen Akram,Shabnum Shaheen,Fouzia Ahmed,Sarah Iqbal +8 more
- 25 Sep 2009
TL;DR: The goal is to develop an ICT tool to assist non-specialist biologist researcher users in performing analysis of large amounts of data by applying simple simulation techniques for better prediction and recommendation in breast cancer analysis.
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Formal modeling and analysis of the hexosamine biosynthetic pathway: role of O-linked N-acetylglucosamine transferase in oncogenesis and cancer progression
Muhammad Tariq Saeed,Jamil Ahmad,Jamil Ahmad,Shahzina Kanwal,Andreana N. Holowatyj,Iftikhar Ali Sheikh,Rehan Zafar Paracha,Aamir Shafi,Aamir Shafi,Amnah Siddiqa,Zurah Bibi,Mukaram Khan,Amjad Ali +12 more
TL;DR: The findings suggest that the OGT and c-Myc feedback loop is critical in tumor progression, and targeting these mediators may provide a mechanism-based therapeutic approach to regulate hyper-O-GlcNAcylation in human cancer.
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