Ambre Bender
University of Strasbourg
13 Papers
40 Citations
Ambre Bender is an academic researcher from University of Strasbourg. The author has contributed to research in topics: DNA methylation & Biology. The author has an hindex of 8, co-authored 13 publications. Previous affiliations of Ambre Bender include Centre national de la recherche scientifique & French Institute of Health and Medical Research.
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Papers
Ontogeny of CpG island methylation and specificity of DNMT3 methyltransferases during embryonic development in the mouse
TL;DR: It is revealed that the DNMT3 de novo methyltransferases play both redundant and specific functions in the establishment of DNA methylation in the mouse embryo.
Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity
Thomas Dahlet,Thomas Dahlet,Andrea Argüeso Lleida,Andrea Argüeso Lleida,Hala Al Adhami,Hala Al Adhami,Michael Dumas,Michael Dumas,Ambre Bender,Ambre Bender,Richard Patryk Ngondo,Richard Patryk Ngondo,Manon Tanguy,Manon Tanguy,Judith Vallet,Judith Vallet,Ghislain Auclair,Ghislain Auclair,Anaïs F. Bardet,Anaïs F. Bardet,Michael Weber,Michael Weber +21 more
TL;DR: By analyzing severely hypomethylated embryos, the authors uncover multiple functions of DNA methylation that is used as a mechanism of repression for a panel of genes including not only imprinted and germline genes, but also lineage-committed genes and 2-cell genes.
DNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice.
Laurianne Scourzic,Lucile Couronné,Marianne Terndrup Pedersen,V Della Valle,M'Boyba Diop,Elena Mylonas,Julien Calvo,Enguerran Mouly,Cécile K. Lopez,Cécile K. Lopez,Cécile K. Lopez,N Martin,Michaela Fontenay,Ambre Bender,Sylvain Guibert,Patrice Dubreuil,Philippe Dessen,Nathalie Droin,Françoise Pflumio,Michael Weber,P. Gaulard,P. Gaulard,Kristian Helin,Thomas Mercher,Thomas Mercher,Thomas Mercher,O. Bernard +26 more
TL;DR: The data confirm the transformation potential of DNMT3AR882H Tet2−/− progenitors and represent the first cooperative model in mice involving Tet2 inactivation driving lymphoid malignancies.
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Heterochromatin establishment at pericentromeres depends on nuclear position
TL;DR: The results indicate that reprogramming of pericentromeric heterochromatin is functionally linked to its nuclear localization, and this results in defective silencing and impaired development.
Non-centrosomal epidermal microtubules act in parallel to LET-502/ROCK to promote C. elegans elongation
Sophie Quintin,Shahoe Wang,Julien Pontabry,Ambre Bender,François Robin,Vincent Hyenne,Frédéric Landmann,Christelle Gally,Karen Oegema,Michel Labouesse +9 more
TL;DR: In this article, the authors investigated the organization of the non-centrosomal microtubule arrays present in the epidermis and assessed their function in elongation, showing that the microtubules were essential for elongation when hemidesmosomes or the activity of the Rho kinase LET-502/ROCK were partially compromised.