Amber Brown
University of Technology, Sydney
21 Papers
24 Citations
Amber Brown is an academic researcher from University of Technology, Sydney. The author has contributed to research in topics: Epigenetics & Regulation of gene expression. The author has an hindex of 9, co-authored 20 publications. Previous affiliations of Amber Brown include Florida State University & University of North Florida.
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Papers
Social isolation alters behavior, the gut-immune-brain axis, and neurochemical circuits in male and female prairie voles.
Meghan Donovan,Meghan Donovan,Meghan Donovan,Calvin S. Mackey,Grayson N. Platt,Jacob Rounds,Amber Brown,Darryl J. Trickey,Yan Liu,Kathryn M. Jones,Zuoxin Wang +10 more
TL;DR: The data suggest that social isolation alters the gut-immune-brain axis in a sex-dependent manner and that gut microbes, central glial cells, and neurochemical systems may play a critical, integrative role in mediating negative outcomes from social isolation.
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Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors.
Jian Feng,Jian Feng,Catherine Jensen Pena,Immanuel Purushothaman,Olivia Engmann,Deena M. Walker,Amber Brown,Orna Issler,Marie A. Doyle,Eileen Harrigan,Ezekiell Mouzon,Vincent Vialou,Li Shen,Meelad M. Dawlaty,Rudolf Jaenisch,Eric J. Nestler +15 more
TL;DR: A novel role for TET1, an enzyme important for DNA hydroxymethylation, in the brain's reward circuitry in modulating stress responses in mice is revealed and a subset of genes that are regulated by TET 1 in this circuitry are identified.
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Detection of cyanotoxins (microcystins/nodularins) in livers from estuarine and coastal bottlenose dolphins (Tursiops truncatus) from Northeast Florida.
TL;DR: The results indicate that both estuarine and coastal dolphins are exposed to MCs/NODs, with potential toxic and immune health impacts.
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Drug Addiction and DNA Modifications.
Amber Brown,Jian Feng +1 more
TL;DR: The functions of DNA modifications and methods for detecting them are discussed, followed by a description of the research investigating the function and consequences of drug-induced changes in DNA methylation patterns.
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Nucleosome Repositioning: A Novel Mechanism for Nicotine- and Cocaine-Induced Epigenetic Changes
TL;DR: It is suggested that nucleosome repositioning represents an initial dynamic genome-wide alteration of the transcriptional landscape preceding more selective downstream transcriptional reprogramming, which ultimately characterizes the cell- and tissue-specific responses to drugs of abuse.
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