Amar Ajmal
Abdul Wali Khan University Mardan
14 Papers
Amar Ajmal is an academic researcher from Abdul Wali Khan University Mardan. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications.
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Papers
Identification of novel inhibitors for SARS-CoV-2 as therapeutic options using machine learning-based virtual screening, molecular docking and MD simulation
Abdus Samad,Amar Ajmal,Arif Mahmood,Beenish Khurshid,Ping Li,Syed Mansoor Jan,Ashfaq Ur Rehman,Pei He,Ashraf N. Abdalla,Muhammad Umair,Junjian Hu,Abdul Wadood +11 more
TL;DR: In this paper , a machine learning-based virtual screening was performed to predict the active phytochemicals against the SARS-CoV-2 3-Chymotrypsin-like protease (3CLPRO), which can be used as a potential drug target.
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Synthesis of new bis(dimethylamino)benzophenone hydrazone for diabetic management: In-vitro and in-silico approach
Momin Khan,Ghulam Ahad,Aftab Alam,Saeed Ullah,Ajmal Khan,Kanwal,Uzma Salar,A. Wadood,Amar Ajmal,Khalid Mohammed Khan,Shahnaz Perveen,Jalal Uddin,Ahmed Al-Harrasi +12 more
TL;DR: Bis(dimethylamino)benzophenone derivatives 1–27 were synthesized from bis(dimethylamino)benzophenone via two-step reaction and were found to be non-toxic on human fibroblast cell lines (BJ cell lines).
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Computer-assisted drug repurposing for thymidylate kinase drug target in monkeypox virus
Amar Ajmal,Arif Mahmood,Chandni Hayat,Mohammed Ageeli Hakami,Bader S. Alotaibi,Muhammad Umair,Ashraf N. Abdalla,Ping Li,Pei He,Abdul Wadood,Junjian Hu +10 more
TL;DR: In this article , the Mpox protein thymidylate kinase (A48R) was targeted because it is a unique drug target, and the results revealed that compound DB16335 revealed the best docking score (-9.57 kcal/mol) against Mpox Protein Thymylate Kinase.
Novel flurbiprofen clubbed oxadiazole derivatives as potential urease inhibitors and their molecular docking study
Sajjad Ahmad,Momin Khan,Aftab Alam,Amar Ajmal,Abdul Wadood,Azim. Khan,A. Alasmari,Metab Alharbi,Abdulrahman Alshammari,Abdul Shakoor +9 more
TL;DR: Twenty eight novel oxadiazole derivatives of the marketed available non-steroidal anti-inflammatory drug (NSAID), (S)-flurbiprofen, were synthesized via I2 mediated cyclo-addition reaction in better yields and were found to be excellent inhibitors of urease enzyme.
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