Amanda J. Russell
Garvan Institute of Medical Research
38 Papers
140 Citations
Amanda J. Russell is an academic researcher from Garvan Institute of Medical Research. The author has contributed to research in topics: Biology & Ubiquitin ligase. The author has an hindex of 18, co-authored 33 publications. Previous affiliations of Amanda J. Russell include University of New South Wales.
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Papers
ABCA Transporter Gene Expression and Poor Outcome in Epithelial Ovarian Cancer
Ellen L. Hedditch,Bo Gao,Amanda J. Russell,Yi Lu,Catherine Emmanuel,Jonathan Beesley,Sharon E. Johnatty,Xiaoqing Chen,Paul R. Harnett,Joshy George,Rebekka T. Williams,Claudia Flemming,Diether Lambrechts,Evelyn Despierre,Sandrina Lambrechts,Ignace Vergote,Beth Y. Karlan,Jenny Lester,Sandra Orsulic,Christine Walsh,Peter A. Fasching,Peter A. Fasching,Matthias W. Beckmann,Arif B. Ekici,Alexander Hein,Keitaro Matsuo,Satoyo Hosono,Toru Nakanishi,Yasushi Yatabe,Tanja Pejovic,Yukie Bean,Florian Heitz,Florian Heitz,Philipp Harter,Andreas du Bois,Ira Schwaab,Estrid Høgdall,S.K. Kjaer,Allan Jensen,Claus Høgdall,Lene Lundvall,Svend Aage Engelholm,Bob Brown,James M. Flanagan,Michelle D Metcalf,Nadeem Siddiqui,Thomas A. Sellers,Brooke L. Fridley,Julie M. Cunningham,Joellen M. Schildkraut,Ed Iversen,Rachel Palmieri Weber,Andrew Berchuck,Ellen L. Goode,David D.L. Bowtell,Georgia Chenevix-Trench,Anna deFazio,Murray D. Norris,Stuart MacGregor,Michelle Haber,Michelle J. Henderson +60 more
TL;DR: In this article, the relationship between clinical outcomes and ABC transporter gene expression in two independent cohorts of high-grade serous EOC tumors was assessed with real-time quantitative polymerase chain reaction, analysis of expression microarray data, and immunohistochemistry.
ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux
Michelle J. Henderson,Michelle Haber,Antonio Porro,Antonio Porro,Marcia A. Munoz,Nunzio Iraci,Chengyuan Xue,Jayne Murray,Claudia Flemming,Janice Smith,Jamie I. Fletcher,Samuele Gherardi,Chin Kiat Kwek,Amanda J. Russell,Emanuele Valli,Wendy B. London,Allen Buxton,Lesley J. Ashton,Alan C. Sartorelli,Susan L. Cohn,Manfred Schwab,Glenn M. Marshall,Giovanni Perini,Murray D. Norris +23 more
TL;DR: ABCC transporters can affect neuroblastoma biology independently of their role in chemotherapeutic drug efflux, enhancing their potential as targets for therapeutic intervention.
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Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma
Laura D. Gamble,Stefania Purgato,Jayne Murray,Lin Xiao,Denise M. T. Yu,Kimberley M. Hanssen,Federico M. Giorgi,Daniel R. Carter,Daniel R. Carter,Andrew J. Gifford,Emanuele Valli,Giorgio Milazzo,Alvin Kamili,Chelsea Mayoh,Bing Liu,Georgina L. Eden,Sara Sarraf,Sophie Allan,Simone Di Giacomo,Claudia Flemming,Amanda J. Russell,Belamy B. Cheung,André Oberthuer,Wendy B. London,Matthias Fischer,Toby Trahair,Toby Trahair,Jamie I. Fletcher,Glenn M. Marshall,Glenn M. Marshall,David S. Ziegler,David S. Ziegler,Michael D. Hogarty,Mark R. Burns,Giovanni Perini,Murray D. Norris,Michelle Haber +36 more
TL;DR: Inhibiting polyamine uptake with the small-molecule drug AMXT 1501, in combination with DFMO, prevented or delayed tumor development in neuroblastoma-prone mice and extended survival in rodent models of established tumors.
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EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response.
Michelle J. Henderson,Amanda J. Russell,Samantha L. Hird,Marcia A. Munoz,Jennifer L. Clancy,Gillian M. Lehrbach,Sophina T Calanni,David A. Jans,David A. Jans,Robert L. Sutherland,Colin K. W. Watts +10 more
TL;DR: A role for EDD in PR signaling is demonstrated but also a link to cancer through DNA damage response pathways is suggested, which is comparable with that of the coactivator SRC-1.
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Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody
Mandeep Singh,Katherine J. L. Jackson,Jing J. Wang,Peter R. Schofield,Peter R. Schofield,Matthew A. Field,Matthew A. Field,David Koppstein,Tim J Peters,Deborah L. Burnett,Deborah L. Burnett,Simone Rizzetto,Damien Nevoltris,Damien Nevoltris,Etienne Masle-Farquhar,Etienne Masle-Farquhar,Megan L. Faulks,Amanda J. Russell,Divya Gokal,Asami Hanioka,Asami Hanioka,Keisuke Horikawa,Alexander D. Colella,Tim Chataway,James Blackburn,James Blackburn,Tim R. Mercer,Tim R. Mercer,David B. Langley,D. Margaret Goodall,Roy Jefferis,Muralikrishna Gangadharan Komala,Anthony D. Kelleher,Dan Suan,Dan Suan,Maureen Rischmueller,Daniel Christ,Daniel Christ,Robert Brink,Robert Brink,Fabio Luciani,Fabio Luciani,Tom P. Gordon,Christopher C. Goodnow,Christopher C. Goodnow,Joanne H. Reed,Joanne H. Reed +46 more
TL;DR: Single-cell multi-omics analysis demonstrates a shared mechanism with lymphoid malignancy in the formation of public rheumatoid factor autoantibodies responsible for mixed cryoglobulinemic vasculitis.
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