Allen Zheng
Icahn School of Medicine at Mount Sinai
8 Papers
Allen Zheng is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Neuraminidase & Virus. The author has an hindex of 5, co-authored 8 publications.
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Papers
Convalescent plasma treatment of severe COVID-19: a propensity score-matched control study.
Sean T. H. Liu,Hung-Mo Lin,Ian Baine,Ania Wajnberg,Jeffrey P. Gumprecht,Farah Rahman,Denise Rodriguez,Pranai Tandon,Adel Bassily-Marcus,Jeffrey Bander,Charles Sanky,Amy C. Dupper,Allen Zheng,Freddy T. Nguyen,Fatima Amanat,Daniel Stadlbauer,Deena R. Altman,Benjamin K. Chen,Florian Krammer,Damodara Rao Mendu,Adolfo Firpo-Betancourt,Matthew A. Levin,Emilia Bagiella,Arturo Casadevall,Carlos Cordon-Cardo,Jeffrey S. Jhang,Suzanne Arinsburg,David Reich,Judith A. Aberg,Nicole M. Bouvier +29 more
TL;DR: Convalescent plasma is potentially effective against COVID-19, but adequately powered, randomized controlled trials are needed.
Enhancing Neuraminidase Immunogenicity of Influenza A Viruses by Rewiring RNA Packaging Signals.
Allen Zheng,Weina Sun,Xiaoli Xiong,Alec W. Freyn,Julia Peukes,Shirin Strohmeier,Raffael Nachbagauer,John A. G. Briggs,Florian Krammer,Peter Palese +9 more
TL;DR: The results provide evidence that the immunodominance of HA stems in part from its abundance on the viral surface, and that rewiring viral packaging signals—thereby increasing the NA content on viral particles—is a viable strategy for improving the immunogenicity of NA in an influenza virus vaccine.
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Nasopharyngeal Type-I Interferon for Immediately Available Prophylaxis Against Emerging Respiratory Viral Infections.
Amos Chungwon Lee,Yunjin Jeong,Sumin Lee,Haewook Jang,Allen Zheng,Sunghoon Kwon,John E. Repine +6 more
TL;DR: In this article, a rationale for developing and testing intranasal interferon beta (IFN-β) as an immediately available intervention for new respiratory viral infections that will arise unexpectedly in the future is presented and supported by basic and clinical trial observations.
Patent
Influenza virus neuraminidase and uses thereof
Peter Palese,Adolfo Garcia-Sastre,Florian Krammer,Brocker Felix,Allen Zheng,Weina Sun +5 more
- 30 Dec 2020
TL;DR: In this article, the mutated influenza virus neuraminidase polypeptides are defined, and a first-stalk domain of the first-person influenza virus is defined.
An electronic antimicrobial stewardship intervention reduces inappropriate parenteral antibiotic therapy
Sean T. H. Liu,Mark J. Bailey,Allen Zheng,Patricia Saunders-Hao,Adel Bassily-Marcus,Maureen Harding,Meenakshi Rana,Roopa Kohli-Seth,Gopi Patel,Shirish Huprikar,Talia H. Swartz +10 more
TL;DR: Close monitoring of broad-spectrum antibiotic use and antibiotic deescalation should occur if interventions to limit blood culture testing are implemented and interventions should include all providers, including consulting physicians.