Aliyah Carson
University of California, San Diego
4 Papers
Aliyah Carson is an academic researcher from University of California, San Diego. The author has contributed to research in topics: TFAM & Mitochondrial biogenesis. The author has an hindex of 3, co-authored 3 publications.
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Papers
Beta amyloid levels in cerebrospinal fluid of HIV-infected people vary by exposure to antiretroviral therapy.
Jerel Adam Fields,Mary K Swinton,Benchawanna Soontornniyomkij,Aliyah Carson,Cristian L. Achim +4 more
TL;DR: Postmortem CSF collected from 70 well-characterized HIV+ decedents was analyzed and suggest that ART exposure is associated with increased levels of Aβ1-42 and A β1-40 in the CSF, potentially suggesting impaired clearance.
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Structural epitope profiling identifies antibodies associated with critical COVID-19 and long COVID
Patrick K. A. Kearns,Mihaly Badonyi,K. Lee,O. Fleming,L. Gerasimivicous,Sabrina Benton,J. Guy,Skot Neilson,Helen Wise,Scott A. Jenks,Kate Templeton,Christina Dold,Teresa Lambe,Alexander J. Mentzer,Jo Knight,A. Pollard,Combat,Madhvi Menon,Tracy Hussell,Circo,Laura McWhirter,Aliyah Carson,Rennos Fragkoudis,Stuart Rosser,David R. Cavanagh,James A. Marsh,Dirk A. Kleinjan,Nguepidjo Gilbert +27 more
TL;DR: This work identifies patterns of antibodies associated with immunopathology, including a non-isotype switching IgM response to a membrane protein epitope strongly associated with severe COVID-19 and suggests the mechanism is T independent B cell activation.
Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice
Jerel Adam Fields,Mary K Swinton,Aliyah Carson,Benchawanna Soontornniyomkij,Charmaine Lindsay,May Madi Han,Katie E. Frizzi,Shrey Sambhwani,Anne N. Murphy,Cristian L. Achim,Ronald J. Ellis,Nigel A. Calcutt +11 more
TL;DR: It is demonstrated that TDF causes peripheral neuropathy in mice and alterations in inflammatory signaling and mitochondrial activity in the brain and dose-dependent increase in oxygen consumption rate, extracellular acidification rate and spare respiratory capacity.
Mitochondrial biogenesis is altered in HIV+ brains exposed to ART: Implications for therapeutic targeting of astroglia.
Mary K Swinton,Aliyah Carson,Francesca Telese,Ana B. Sanchez,Benchawanna Soontornniyomkij,Leila Rad,Isabella B. Batki,Brandi Quintanilla,Josué Pérez-Santiago,Cristian L. Achim,Scott Letendre,Ronald J. Ellis,Igor Grant,Anne N. Murphy,Jerel Adam Fields +14 more
TL;DR: Results show that mitochondrial biogenesis is differentially regulated in neurons and astroglia in HAND brains and that targeting astroglial bioenergetic processes may be a strategy to modulate neuroinflammation.