Alison H. Goodall
University of Leicester
200 Papers
5.1K Citations
Alison H. Goodall is an academic researcher from University of Leicester. The author has contributed to research in topics: Platelet & Platelet activation. The author has an hindex of 65, co-authored 197 publications. Previous affiliations of Alison H. Goodall include Leicester Royal Infirmary & AMIT.
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Papers
Therapeutic Benefit of Low-Dose Clopidogrel in Patients Undergoing Carotid Surgery Is Linked to Variability in the Platelet Adenosine Diphosphate Response and Patients’ Weight
TL;DR: These results explain how a single 75-mg dose of clopidogrel produces a significant clinical impact on embolization.
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Platelet inhibition by aspirin is diminished in patients during carotid surgery: a form of transient aspirin resistance?
David A. Payne,Chris I. Jones,Paul D. Hayes,Sally E. Webster,Ross Naylor A,Alison H. Goodall +5 more
- 01 Jul 2004
TL;DR: The antiplatelet activity of aspirin diminished significantly during surgery, but was partially restored by the end of the procedure without additional aspirin treatment, which may explain why some patients undergoing cardiovascular surgery remain at risk of peri-operative stroke and myocardial infarction.
19
Thrombus Size and Doppler Embolic Signal Intensity
Matthew J. Martin,Emma M.L. Chung,Kumar V. Ramnarine,Alison H. Goodall,A. Ross Naylor,David H. Evans +5 more
TL;DR: Experimental evidence supporting theoretical predictions relating Doppler embolic signal intensity to thrombus size is provided and it is tentatively suggested how this information might be used to size emboli in clinical practice.
Transient heparin-induced platelet activation linked to generation of platelet 12-lipoxygenase. Findings from a randomised controlled trial.
TL;DR: Heparin administration during CEA generates AA that is metabolised to 12-HETE via the 12-LOX pathway, possibly explaining the phenomenon of transient heparin-induced platelet activation.
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Leukotriene B4 production in healthy subjects carrying variants of the arachidonate 5-lipoxygenase-activating protein gene associated with a risk of myocardial infarction
Annette Maznyczka,Massimo Mangino,Andrew Whittaker,Peter S. Braund,Tom Palmer,Martin D. Tobin,Alison H. Goodall,Peter Bradding,Nilesh J. Samani +8 more
TL;DR: In this paper, the authors presented a Clinical Science, 2007, 112 (7), pp. 411-416, and the paper is available from http://www.clinsci.org/cs/112/cs1120411.htm.