Alice Topping
6 Papers
9 Citations
Alice Topping is an academic researcher. The author has contributed to research in topics: Hemodialysis & Medicine. The author has an hindex of 3, co-authored 6 publications.
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Papers
Lipid levels are inversely associated with infectious and all-cause mortality: international MONDO study results
George A. Kaysen,Xiaoling Ye,Jochen G. Raimann,Yuedong Wang,Alice Topping,Len A. Usvyat,Stefano Stuard,Bernard Canaud,Frank M. van der Sande,Jeroen P. Kooman,Peter Kotanko +10 more
TL;DR: Low LDL-C was associated with reduced all-cause and infectious, but not CV mortality, which resulted in the inverse association with all- Cause mortality, and higher LDL- C, HDL-C, and TGs were independently associated with lower all- cause death risk.
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The Virtual Anemia Trial: An Assessment of Model-Based In Silico Clinical Trials of Anemia Treatment Algorithms in Patients With Hemodialysis.
Doris H. Fuertinger,Alice Topping,Franz Kappel,Stephan Thijssen,Peter Kotanko +4 more
- 01 Apr 2018
TL;DR: The novel strategies presented here, aimed to improve external and ecological validity of a VCT, significantly increased the predictive power of the discussed in silico trial.
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A Cross-Sectional Study of Growth and Metabolic Bone Disease in a Pediatric Global Cohort Undergoing Chronic Hemodialysis.
Rasha Hussein,Ana Catalina Alvarez-Elías,Alice Topping,Jochen G. Raimann,Guido Filler,Dalia Yousif,Peter Kotanko,Len A. Usvyat,Mara Medeiros,Roberto Pecoits-Filho,Bernard Canaud,Stefano Stuard,Xu Xiaoqi,Michael Etter,Maria E. Ferris +14 more
TL;DR: North America had the best growth, received the most dialysis, but also had the worst phosphate control and body mass index z scores, and regional differences in growth‐ and age‐adjusted bone mineral metabolism markers were found.
8
Association between Heights of Dialysis Patients and Outcomes: Results from a Retrospective Cohort Study of the International MONitoring Dialysis Outcomes (MONDO) Database Initiative
Samir S. Patel,Alice Topping,Xiaoling Ye,Hanjie Zhang,Bernard Canaud,Paola Carioni,Christina Marelli,Adrian Guinsburg,Albert Power,Neill Duncan,Jeroen P. Kooman,van der Sande F,Len A. Usvyat,Yuedong Wang,Xiaoqi Xu,Peter Kotanko,Jochen G. Raimann +16 more
TL;DR: An increasing risk of death with increasing height is found in all regions, except North America, while the reasons remain unclear, and further research may be warranted.
Patent
Techniques for conducting virtual clinical trials
Doris H. Fuertinger,Alice Topping,Franz Kappel,Stephan Thijssen,Peter Kotanko +4 more
- 17 Jan 2019
TL;DR: In this article, the authors describe techniques and apparatus for generating, performing, and evaluating virtual clinical trials that include clinic modules to represent real-world operational aspects of the trial entities.