Alice S. Chau
Seattle Children's Research Institute
8 Papers
22 Citations
Alice S. Chau is an academic researcher from Seattle Children's Research Institute. The author has contributed to research in topics: Tocilizumab & Dornase alfa. The author has an hindex of 5, co-authored 7 publications.
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Papers
Comparative Survival Analysis of Immunomodulatory Therapy for Coronavirus Disease 2019 Cytokine Storm.
Sonali Narain,Dimitre G. Stefanov,Alice S. Chau,Andrew G. Weber,Galina Marder,Blanka Kaplan,Prashant Malhotra,Ona Bloom,Ona Bloom,Audrey Liu,Martin Lesser,Negin Hajizadeh,Negin Hajizadeh,Stuart L. Cohen,Jennifer Cookingham,David Hirschwerk,Naomi I Maria,Sanjaya K. Satapathy,Cristina Sison,Matthew D. Taylor,Michael Qiu +20 more
TL;DR: The combination of corticosteroid use either alone or in combination with tocilizumab or anakinra was associated with reduced hospital mortality for patients with COVID-19 cytokine storm compared to standard of care.
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Comparative Survival Analysis of Immunomodulatory Therapy for COVID-19 'Cytokine Storm': A Retrospective Observational Cohort Study
TL;DR: In this paper, Cytokine storm is a marker of COVID-19 illness severity and increased mortality and immunomodulatory treatments have been repurposed to improve mort
Comparative Survival Analysis of Immunomodulatory Therapy for COVID-19 'Cytokine Storm': A Retrospective Observational Cohort Study
Sonali Narain,Dimitre G. Stefanov,Alice S. Chau,Andrew G. Weber,Galina Marder,Blanka Kaplan,Prashant Malhotra,Ona Bloom,Audrey Liu,Martin Lesser,Negin Hajizadeh +10 more
TL;DR: Corticosteroid and tocilizumab used in combination, or corticosteroids alone, was associated with reduced hospital mortality for patients with COVID-19 cytokine storm and improved hospital survival compared to standard of care.
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•Journal Article
Comparative Survival Analysis of Immunomodulatory Therapy for COVID-19 'Cytokine Storm'
Sonali Narain,Dimitre G. Stefanov,Alice S. Chau,Andrew G. Weber,Galina Marder,Blanka Kaplan,Prashant Malhotra,Ona Bloom,Audrey Liu,Martin Lesser,Negin Hajizadeh,Stuart L. Cohen,Jennifer Cookingham,David Hirschwerk,Naomi I Maria,Sanjaya K. Satapathy,Cristina Sison,Matthew D. Taylor,Michael Qiu +18 more
TL;DR: In this article, the authors conducted a retrospective analysis of electronic health records across the Northwell Health system COVID-19 patients hospitalized between March 1, 2020 and April 24, 2020 were included Cytokine storm was defined by inflammatory markers: ferritin >700ng/mL, C-reactive protein >30mg/dL or lactate dehydrogenase >300U/L.
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