Alexandre S. Stephens
University of Sydney
39 Papers
283 Citations
Alexandre S. Stephens is an academic researcher from University of Sydney. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 13, co-authored 35 publications. Previous affiliations of Alexandre S. Stephens include Griffith University & Southern Cross University.
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Papers
Internal control genes for quantitative RT-PCR expression analysis in mouse osteoblasts, osteoclasts and macrophages
TL;DR: The selection of a concise set of housekeeper genes suitable to use as normalization factors for quantitative real-time RT-PCR gene expression studies in osteoblasts, osteoclasts and macrophages is reported on.
Temporal pattern of gene expression and histology of stress fracture healing
Lisa Kidd,Alexandre S. Stephens,Julia S. Kuliwaba,Nicola L. Fazzalari,Andy Wu,Mark R. Forwood +5 more
TL;DR: In this article, a detailed examination of the histology, histomorphometry and gene expression of the healing and remodelling process initiated by fatigue loading of the rat ulna was conducted.
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•Journal Article
Temporal pattern of gene expression and histology of stress fracture healing in the rat ulna-loading model
TL;DR: Dramatic, early upregulation of IL-6 and IL-11 demonstrate their central role in initiating signalling events for remodelling and stress fracture healing.
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Association of Functionally Different RUNX2 P2 Promoter Alleles With BMD
James D. Doecke,Christopher J. Day,Alexandre S. Stephens,Shea L. Carter,Angela van Daal,Mark A. Kotowicz,Geoff Nicholson,Nigel Alexander Morrison +7 more
TL;DR: RUNX2 gene SNPs were genotyped in subjects from the upper and lower deciles of age‐ and weight‐adjusted femoral neck BMD and only SNPs in the P2 promoter were significantly associated with BMD.
56
Myocyte Enhancer Factor 2C, an Osteoblast Transcription Factor Identified by Dimethyl Sulfoxide (DMSO)-enhanced Mineralization
Alexandre S. Stephens,Sebastien Robert Stephens,Carol Hobbs,Deitmar W. Hutmacher,Desa Bacic-Welsh,Maria A. Woodruff,Nigel Alexander Morrison +6 more
TL;DR: In primary human osteoblasts, DMSO dose-dependently enhanced the expression of osteoblast differentiation markers alkaline phosphatase activity and extracellular matrix mineralization and a flow on knockdown of bone-specific transcription factors, Runx2 and osterix, suggests that Mef2c lies upstream of these two important factors in the cascade of gene expression in osteoblast.
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