Alexandra Dreesman
Université libre de Bruxelles
12 Papers
35 Citations
Alexandra Dreesman is an academic researcher from Université libre de Bruxelles. The author has contributed to research in topics: Tuberculosis & Medicine. The author has an hindex of 4, co-authored 8 publications. Previous affiliations of Alexandra Dreesman include Free University of Brussels.
Chat about Author
Papers
Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia
Ana García-García,Rebeca Pérez de Diego,Carlos Flores,Darawan Rinchai,Jordi Solé-Violán,Angela Deyà-Martínez,Blanca García-Solis,José M. Lorenzo-Salazar,Elisa Hernández-Brito,Anna-Lisa Lanz,Leen Moens,Giorgia Bucciol,Mohamed A Almuqamam,Joseph B. Domachowske,Elena Colino,Juan Luis Santos-Perez,Francisco Marco,Claudio Pignata,Aziz Bousfiha,Stuart E. Turvey,S. Baur,Filomeen Haerynck,Javier Gonzalo Ocejo-Vinyals,Francisco Lendínez,Seraina Prader,Nora Naumann-Bartsch,Jana Pachlopnik Schmid,Catherine M. Biggs,Kyla J. Hildebrand,Alexandra Dreesman,Miguel Angel Cárdenes,Fatima Ailal,Ibtihal Benhsaien,Giuliana Giardino,Águeda Molina-Fuentes,Claudia Fortuny,Swetha Madhavarapu,Daniel H. Conway,Carolina Prando,Laire Schidlowski,María Teresa Martínez de Saavedra Álvarez,Rafael Alfaro,Felipe Rodríguez de Castro,Isabelle Meyts,Fabian Hauck,Anne Puel,Paul Bastard,Bertrand Boisson,Emmanuelle Jouanguy,Laurent Abel,Aurélie Cobat,Qian Zhang,Jean-Laurent Casanova,Laia Alsina,Carlos Rodríguez-Gallego +54 more
TL;DR: MyD88 and IRAK-4-deficient patients have a higher risk of hypoxemic COVID-19 pneumonia than individuals of similar age in the general population, due to impaired TLR7-dependent type I IFN production as mentioned in this paper .
Age-Stratified T Cell Responses in Children Infected with Mycobacterium tuberculosis.
Alexandra Dreesman,Véronique Corbière,Violette Dirix,Kaat Smits,Sara Debulpaep,Iris De Schutter,Myriam Libin,Mahavir Singh,Anne Malfroot,Camille Locht,Françoise Mascart +10 more
TL;DR: HBHA-induced IL-17 production by CD4+ T lymphocytes was associated with protection only in children under 3 years who are at high risk for rapid progression to aTB, suggesting that the distinction between children with LTBI and those with aTB is possible based on age-related diagnostic markers.
Immunological Signatures Identifying Different Stages of Latent Mycobacterium tuberculosis Infection and Discriminating Latent from Active Tuberculosis in Humans
Kaatje Smits,Véronique Corbière,Violette Dirix,Leila Mekkaoui,Chloe Wyndham-Thomas,Myriam Libin,Alexandra Dreesman,Marc Loyens,Marie-Christine Payen,Mahavir Singh,Camille Locht,Françoise Mascart +11 more
TL;DR: Qualitative and quantitative T cell responses to different mycobacterial antigens in selected populations of infected subjects are characterized to identify new biomarkers that could help to identify M. tuberculosis-infected subjects and to stratify them in risk groups for reactivation of the infection.
16
The impact of Bacille Calmette-Guérin shortage on immunisation practice and policies in Europe - A Paediatric Tuberculosis Network European Trials Group (ptbnet) survey.
Antti Kontturi,Antti Kontturi,Begoña Santiago,Marc Tebruegge,Marc Tebruegge,Marc Tebruegge,Ulrich von Both,Eeva Salo,Nicole Ritz,Nicole Ritz,Daniel Blázquez,Matthias Bogyi,Danilo Buonsenso,Alexandra Dreesman,Uros Krivec,Françoise Mouchet,Sahar Nejat,Olaf Neth,Ivan Pavic,Ezia Ruga,Rupert Schlags,Antoni Soriano-Arandes,Steffi Thee,Maria Tsolia,Svetlana Velizarova +24 more
TL;DR: The BCG shortage in Europe leads to significant changes in immunisation policies including changes of BCG vaccine strain and manufacturer, and infants and children eligible for immunisation are at risk of not receiving BCG.
15
Tuberculosis Transmission in a Primary School and a Private Language School. An Estimation of Infectivity
Sara Debulpaep,Sara Debulpaep,Alexandra Dreesman,Violette Dirix,Véronique Toppet,Maryse Wanlin,Lies Geysens,Wouter Arrazola de Oñate,Maryse Fauville,Françoise Mascart,Jack Levy,Françoise Mouchet +11 more
TL;DR: This exposure investigation of two teachers detects high transmission among family contacts and school casual contacts, and recommendations for chemoprophylactic treatment in children <5 years showed low compliance, reflecting the difficulty of communication to staff, parents, and children in a school outbreak.
6