Alexander Knuettel

TL;DR: In this article, a method for investigating a scattering medium, especially a biological matrix, with intensity-modulated light, is proposed, in which a high-frequency modulation signal is generated by a frequency generator (18), the intensity of a light emitter (10) is modulated with a modulation signal and the light from the emitter is radiated into the medium, the modulation signal includes frequency chirps during which the modulation frequency is tuned from an initial frequency to a final frequency.

Abstract: A low-coherence interferometric device for examining a sample (15), especially for multi-dimensional imaging, with an interferometer arrangement (2) comprising a low-coherence light source, an irradiation head (9) with a light outlet (16) for radiating light into the sample, an optical coupler, a reference reflector and a detector (13), in which the light paths between the components of the interferometer arrangement (2) form interferometer arms. The optical coupler and the reference arm of the interferometer arrangement (2) are integrated into an optical chip (28). In addition to the reference reflector, the reference arm has a deflection reflector constructed on an end surface of the optical chip (28) in such a way that the reference light is coupled across between a first light guide forming a first partial length of the reference arm and a second light guide forming a second partial length of the reference arm.

TL;DR: In this article, the optical coupler and the reference arm of an interferometer configuration are integrated into a common optical chip, in such a way that the reference light is cross-coupled between a first light guide (10 a) forming a first portion of the inter-ferer configuration and a second light guide(10 b) forming the second portion.

TL;DR: In this article, the authors proposed a non-invasive process for the determination of glucose without reagents, where part of the light radiated by the light transmitter was taken via a reference light path with a defined optical length to the light receiver.